Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics

Wu Pensee; Mamas Mamas A.; Gulati Martha

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Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics

机译：怀孕作为孕产妇心血管疾病的预测因子：心肺体外的时代

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Globally, cardiovascular disease (CVD) is the most common cause of mortality in women accounting for one in three deaths. There remains an under recognition of CVD as well as a lack of awareness of risk in women. Promotion of CVD prevention is essential, but the current risk assessment tools do not incorporate any sex-specific cardiovascular risk factors. There is increasing recognition of sex-specific risk factors that appear during pregnancy that are associated with CVD. These adverse pregnancy outcomes (APOs) include preeclampsia, gestational hypertension, preterm birth, gestational diabetes, delivery of a small-for-gestational-age infant, miscarriage, and high parity number. Although the underlying biological mechanism for these association remains to be elucidated, current international guidelines are beginning to recommend the inclusion of APOs in the assessment of CVD risk in women. This review summarizes the evidence for the association between APOs and future CVD. It also highlights the importance of considering APOs in the cardiovascular risk assessment, specifically in young women, allowing for targeted lifestyle-modifying interventions with the potential to alter their risk trajectory and improve their long-term cardiovascular health.

机译：全球性，心血管疾病（CVD）是三分之一死亡中占妇女死亡率最常见的原因。仍然有一个识别CVD以及缺乏对女性风险的意识。促进CVD预防是必不可少的，但目前的风险评估工具不含有任何性特异性心血管危险因素。越来越严重识别与CVD相关的怀孕期间出现的性别特异性风险因素。这些不良妊娠结果（apos）包括预坦克敏，妊娠期高血压，早产，妊娠期糖尿病，递送小于胎儿的婴儿，流产和高奇偶阶级。虽然这些关联的潜在生物机制仍有待阐明，但目前的国际指南开始建议将APO列入妇女的CVD风险的评估。本综述总结了APO和未来CVD之间关联的证据。它还强调了考虑在缺血风险评估中，特别是在年轻女性中的重要性，允许有针对性的生活方式修改干预措施，潜力可以改变其风险轨迹并改善他们的长期心血管健康。

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《Journal of women’s health》 |2019年第8期|共14页
作者
Wu Pensee; Mamas Mamas A.; Gulati Martha;
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作者单位

Univ Keele Keele Cardiovasc Res Grp Ctr Prognosis Res Inst Primary Care &

Hlth Sci Stoke On;

Univ Keele Keele Cardiovasc Res Grp Ctr Prognosis Res Inst Primary Care &

Hlth Sci Stoke On;

Univ Arizona Div Cardiol Phoenix AZ USA;

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正文语种 eng
中图分类妇幼卫生;
关键词
cardiovascular disease; pregnancy; gestational hypertension; preterm birth; gestational diabetes;

机译：心血管疾病;妊娠;妊娠期高血压;早产;妊娠期糖尿病;

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1. Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics [J] . Wu Pensee, Mamas Mamas A., Gulati Martha Journal of women’s health . 2019,第8期

机译：怀孕作为孕产妇心血管疾病的预测因子：心肺体外的时代
2. Hypertensive pregnancy disorders increase the risk of maternal cardiovascular disease after adjustment for cardiovascular risk factors [J] . Riise Hilde Kristin Refvik, Sulo Gerhard, Tell Grethe S., International Journal of Cardiology . 2019,第期

机译：高血压妊娠疾病在调整心血管危险因素后增加母体心血管疾病的风险
3. Cardiovascular morbidity and mortality in pregnancy Management challenges in pregnancies complicated by maternal heart disease are complex, requiring ongoing involvement of a team of specialists, [J] . BETH BRICKNER Contemporary ob/gyn . 2018,第1期

机译：孕产妇心脏病复杂的怀孕管理挑战的心血管发病率和死亡率是复杂的，需要持续参与一支专家团队，
4. Imaging of Acute Maternal Diseases in Pregnancy [C] . Andrew J. LeRoy, the Radiological Society of North America Scientific Assembly and Annual Meeting of the Radiological Society of North America . 2006

机译：妊娠期急性母体疾病的成像
5. Maternal prepregnancy nutritional status as a key link of intergenerational risk of obesity and chronic disease in childhood and later life among US Pacific Islanders: A life course approach study. [D] . Techur-Pedro, Angela. 2015

机译：孕产妇的营养状况是美国太平洋岛民中儿童及以后生活中肥胖和慢性病的代际风险的关键链接：一项生命历程方法研究。
6. Pregnancy Complications as Markers for Subsequent Maternal Cardiovascular Disease: Validation of a Maternal Recall Questionnaire [O] . Ebony Boyce Carter, Jennifer J. Stuart, Leslie V. Farland, -1

机译：妊娠并发症作为随后的孕产妇心血管疾病的标志：产妇召回问卷的验证
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机译：心肌变形之间P235Relation通过三维斑点追踪分析，在患者全身hypertensionP236Obstructive睡眠呼吸暂停的高血压和功能的能力控制是经常根据公认在急性心肌梗死，但通常有助于左室舒张dysfunctionP237Intrinsic左心室功能紊乱中白塞氏病与全身性疾病的活性的比较：用于预毛细管的从植入装置和电极数目的毛细血管后肺hypertensionP240The巧合的分化与存在的两个新的超声心动图参数单和双pregnancyP239Proposal期间从斑点追踪echocardiographyP238Echocardiography变化的见解静脉引线后残留的纤维组织提取评估了超声心动图examP241Hemoglobin是绝经后妇女的左心室肥厚的独立预测因素，但不是在premen opausal womenP242Left心室纵向变形损害牛皮癣患者与免疫联activationP243Impaired舒张功能和左心房机械功能患者的心脏和血管功能继发于胰岛素的维生素-d deficiencyP244Modification resistanceP245Impaired右心室功能是不相关的血清半乳凝素3浓度患者右心室（RV）的纵向功能fallotP246Age调整指标的修复四部曲没有充分反映在冠状动脉diseaseP248A追溯血流储备分数和多巴酚丁胺超声心动图之间修复先天性心脏缺陷和RV容积overloadP247Relationship全球儿童RV收缩在术前评估核试验对应力回声的阴性预测值进行可行myocard的实体器官transplantionP249The检测患者的观察对比研究鎓通过多巴酚丁胺斑点跟踪超声心动图在患者的心脏衰竭锻炼期间冠状动脉diseaseP250VO2压扁：证据为一个组合的低心输出量和低效率的O2 extractionP251在心脏衰竭患者运动超声心动图中肺泡 - 毛细血管屏障的动态评估具有降低的喷射对心脏功能的运动锻炼的运动负荷超声过程中患者fractionP252The影响2型糖尿病患者和表面健康受试者的群体在心血管riskP254Difference在功能性二尖瓣返流的semisupine测力计和手柄之间的变化舒张dysfunctionP253Age相关的最大运动O2提取差异环大小的exerciseP255Correlation由回波2D评估，3d和多排的患者正在接受经导管主动脉瓣implantationP256Mitral环动力学计算机断层：从正常到广泛mixomatous疾病三dimensi Onal地区食道studyP257Left心耳闭合：视在左心室功能，质量和（UN）捻基于导管的肾去神经支配的55 casesP258Effect的在外周血单核细胞和左侧的微小RNA基因表达的二维散斑跟踪echocardiographyP259Associations回波点心室全球纵向应变峰值在原发性高血压患者

Pregnancy As a Predictor of Maternal Cardiovascular Disease: The Era of CardioObstetrics

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