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首页> 外文期刊>Journal of women’s health >Gestational Diabetes and Maternal Weight Management During and After Pregnancy
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Gestational Diabetes and Maternal Weight Management During and After Pregnancy

机译：妊娠期糖尿病和孕产妇体重管理期间和怀孕后

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Background: Women diagnosed with gestational diabetes mellitus (GDM) substantially modify their diets during pregnancy to control hyperglycemia. These changes could also affect maternal weight management. Materials and Methods: From July 2014 to December 2015 we enrolled women with and without GDM in a prospective cohort study to compare their mean rates of (1) weight gain before GDM screening, (2) weight gain after GDM screening, and (3) postpartum weight loss. All GDM-affected women were referred to Medical Nutrition Therapy and asked to self-monitor blood glucose until delivery. Rate comparisons were conducted separately for each interval using weighted t-tests and inverse probability of treatment weighting (IPTW) to account for age and prepregnancy body mass index (BMI). Linear regression models were developed to characterize the association of GDM status and rate of weight change. Results: The study included 40 women with GDM and 49 women without GDM. The IPTW analysis found that (1) women with and without GDM had similar mean rates of gestational weight gain before GDM screening (0.41 +/- 0.26 kg/week vs. 0.45 +/- 0.35 kg/week, respectively, p = 0.86), (2) women with GDM gained weight at a significantly lower mean rate than women without GDM following GDM screening (0.30 +/- 0.28 kg/week vs. 0.53 +/- 0.28 kg/week, respectively, p = 0.001), and (3) women with and without GDM had similar mean rates of postpartum weight loss (-1.37 +/- 0.58 kg/week vs. -1.28 +/- 0.46 kg/week, respectively, p = 0.73). The linear regression model (adjusted for age and prepregnancy BMI) demonstrated that women with GDM gained 0.19 kg/week less than women without GDM (p = 0.004) during pregnancy after GDM screening. Conclusions: In the postpartum period, women with GDM lose weight at similar rates to women without GDM despite gaining weight at significantly lower rates following GDM screening. Diagnosis and treatment of GDM may improve maternal weight management, but this benefit is limited to late pregnancy.
机译：背景：被诊断患有妊娠糖尿病的妇女Mellitus（GDM）在怀孕期间大幅改变它们的饮食，以控制高血糖症。这些变化也可能影响母体体重管理。材料与方法：2014年7月至2015年12月，我们在未来的队列研究中注册了妇女，没有GDM，将其平均速率与GDM筛选前（2）重量增益进行比较，（2）GDM筛选后的重量增益，（3）产后减肥。所有GDM受影响的女性都被称为医学营养治疗，并要求自我监测血糖直至交付。使用加权T检验和治疗加权（IPTW）的逆概率分别对每个间隔进行速率比较，以考虑年龄和预妊娠体重指数（BMI）。开发了线性回归模型，以表征GDM状态和重量率变化。结果：该研究包括40名妇女与GDM和49名没有GDM的女性。 IPTW分析发现（1）没有GDM的女性在GDM筛选之前具有类似的妊娠重量增益的平均速率（0.41 +/- 0.26千克/周与0.45 +/- 0.35千克/周，P = 0.86） （2）GDM的妇女在GDM筛选后比没有GDM的女性显着降低的平均速率（0.30 +/- 0.28千克/周与0.53 +/- 0.28kg /周，分别为p = 0.001）， （3）没有GDM的妇女具有类似的产后减肥的平均速率（-1.37 +/- 0.58公斤/周与-1.28 +/- 0.46千克/周，P = 0.73）。线性回归模型（适于年龄和预妊娠BMI）展示了GDM的女性在GDM筛选后怀孕期间没有GDM（P = 0.004）的女性。结论：在产后期间，尽管在GDM筛查后的速率显着降低速度，但患有GDM的女性对没有GDM的女性的重量减肥。 GDM的诊断和治疗可以改善产妇体重管理，但这种益处仅限于怀孕晚期。

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