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Therapeutic effects of antimicrobial compounds against bacillary necrosis of larval pacific oyster

机译:抗菌化合物对幼虫太平洋牡蛎组织性坏死的疗效作用

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摘要

Eight antimicrobial compounds were examined to evaluate their therapeutic effects against experimentally or naturally induced vibriosis of the Pacific oyster Crassostrea gigas. In experimental infections with a strain of Vibrio splendidus biovar II, a causative agent of bacillary necrosis of cultured triploid oyster larvae, chloramphenicol (CP) exhibited complete protection against challenges at 10(5) or 10(6) CFU/mL, and erythromycin (EM), novobiocin (NB), gentamicin and streptomycin (SM) were effective to reduce the mortality, but nalidixic acid or oxytetracycline was not. CP and EM were also highly effective against experimental infections with other six strains of Vibrio species (V. splendidus biovar II, V. pelagius I, V. campbellii, and V. tubiashii) which had been isolated from oyster larvae or the rearing water, but NB and SM were less effective. On the other hand, not only CP and EM but also NB and SM exhibited higher protection against the natural infection.
机译:检查8种抗微生物化合物以评估其对天然或天然诱导的太平洋牡蛎克斯辛西亚吉亚斯的治疗效果。 在实验性感染中具有vibrio splendidus biovar II的菌株,培养的三倍体牡蛎幼虫的致病剂,氯霉素(Cp)具有完全保护,在10(5)或10(6)CFU / mL和红霉素( EM),Novobiocin(NB),庆大霉素和链霉素(SM)有效降低死亡率,但不含萘酸或氧赤霉素不是。 CP和EM也对与其他六种血管种类(V.Plassidus Biovar II,V.Pelagius I,V.Campbellii和V.Camiasshii)的实验感染具有高度有效的患有牡蛎幼虫或饲养水的实验感染 但NB和SM不太有效。 另一方面,不仅CP和EM,而且NB和SM也表现出更高的自然感染保护。

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