Diabetes under control: Understanding oral antidiabetic agents.

Longo R

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Diabetes under control: Understanding oral antidiabetic agents.

机译：糖尿病得到控制：了解口服降糖药。

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With the availability of new oral medications to treat type 2 diabetes, management has become increasingly confusing. Currently, there are six major classes of oral antidi-abetic agents available in the United States: the biguanides, thiazolidinediones (TZDs), sulfonylurea secretagogues, nonsulfonylurea secretagogues, alpha-glucosidase inhibitors, and dipeptidyl-peptidase 4 (DPP-4) inhibitors. Because each class tackles diabetes differently, some classes are more appropriate for certain patients than others. Understanding the pathophysiologic targets of each class and the often subtle differences in the ways they improve glycemic control can make drug selection and disease management less bewildering.

机译：随着新型口服药物可用于治疗2型糖尿病，治疗方法变得越来越混乱。目前，美国有六种主要的口服抗糖尿病药：双胍类，噻唑烷二酮类（TZD），磺酰脲类促分泌剂，非磺酰脲类促分泌剂，α-葡萄糖苷酶抑制剂和二肽基肽酶4（DPP-4）抑制剂。由于每个班级处理糖尿病的方式不同，因此某些班级比其他班级更适合某些患者。了解每个类别的病理生理学目标以及改善血糖控制的方式通常存在细微的差异，可以使药物选择和疾病管理不那么令人困惑。

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《American Journal of Nursing: Official Magazine of the American Nurses' Associstion》 |2010年第2期|共4页
作者
Longo R;
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正文语种 eng
中图分类护理学;
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1. Diabetes under control: Understanding oral antidiabetic agents. [J] . Longo R American Journal of Nursing: Official Magazine of the American Nurses' Associstion . 2010,第2期

机译：糖尿病得到控制：了解口服降糖药。
2. Glycemic control with preprandial versus basal insulin in patients with type 2 diabetes mellitus poorly controlled by oral antidiabetes agents. [J] . Heise T, Mathieu C, Hey Hadavi J, Diabetes technology & therapeutics . 2010,第2期

机译：2型糖尿病患者的餐前和基础胰岛素对血糖的控制很难通过口服降糖药控制。
3. A randomized, open‐label, multicentre, parallel‐controlled study comparing the efficacy and safety of biphasic insulin aspart 30 plus metformin with biphasic insulin aspart 30 monotherapy for type 2 diabetes patients inadequately controlled with oral antidiabetic drugs: The merit study [J] . Guo Lixin, Chen Li, Chang Baocheng, Diabetes, obesity & metabolism . 2018,第12期

机译：随机，开放标签，多期，并行控制的研究比较了双相胰岛素Aspart 30加二甲双胍的疗效和安全性与双相胰岛素Aspart 30单药治疗2型糖尿病患者与口腔抗糖尿病药物不充分控制：优点研究
4. Biocompatible interpolymer complex matrix tablets - an oral sustained release class-Ill antidiabetic drug [C] . S K Ershadul Haque, A Sheela International Conference on Science, Engineering the Technology . 2018

机译：生物相容性互聚合物复合基质片剂 - 口服持续释放类药物抗糖尿病药物
5. The relationship between the emotional burden of Type 2 Diabetes and glycemic control and differences in emotional burden and glycemic control among individuals treated with oral antidiabetic agents, combination therapy, incretin mimetic, and insulin [D] . Douaihy, Katharine 2008

机译：2型糖尿病患者的情绪负担与血糖控制之间的关系以及口服抗糖尿病药，联合疗法，降钙素模拟物和胰岛素治疗的个体之间情绪负担和血糖控制的差异
6. A Single-blind Placebo-controlled Dose-ranging Trial of Oral Hepatic-directed Vesicle Insulin Add-on to Oral Antidiabetic Treatment in Patients With Type 2 Diabetes Mellitus [O] . W. Blair Geho, Len N. Rosenberg, Sherwyn L. Schwartz, 2014

机译：口服肝定向囊泡胰岛素对2型糖尿病患者口服抗糖尿病治疗的单盲安慰剂对照剂量范围试验
7. Addition of Basal Insulin to Oral Antidiabetic Agents in Patients with Inadequately Controlled Type 2 Diabetes Leads to Improved HbA1c Levels: Metabolic Control, Frequency of Hypoglycemia, and Insulin Titration Analysis as Results of a Prospective Observational Study (BALI Study) [O] . Jan Brož, Denisa Janíčková Ždárská, Radka Štěpánová, 2019

机译：对患者2型糖尿病患者的口腔抗糖尿病患者添加基础胰岛素导致HBA1C水平改善：代谢控制，低血糖频率和胰岛素滴定分析作为前瞻性观察研究的结果（巴厘岛研究）

Diabetes under control: Understanding oral antidiabetic agents.

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