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首页> 外文期刊>American Journal of Obstetrics and Gynecology >Black cohosh (Cimicifuga racemosa): a systematic review of adverse events.
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Black cohosh (Cimicifuga racemosa): a systematic review of adverse events.

机译：黑升麻（Cimicifuga racemosa）：对不良事件的系统评价。

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摘要

Black cohosh (Cimicifuga racemosa) is used most often to treat symptoms that can occur during menopause. However, in the last years, several concerns regarding its safety have been voiced. The aim of this systematic review was to evaluate the clinical evidence for or against the safety of black cohosh. Systematic literature searches were conducted in 5 computerized databases (Medline, Embase, Amed, Phytobase, and Cochrane Library). The references of all located articles were scanned for further relevant publications. Any type of clinical data that included case reports and observational studies was considered. No language restrictions were imposed. Thirteen clinical trials (all of which indicated relative safety), 3 postmarketing surveillance studies, 4 case series, and 8 single case reports were identified. Clinical studies suggest black cohosh to be safe. In most case reports, causal attribution is problematic. In conclusion, black cohosh has been associated with serious safety concerns that urgentlyrequire further investigation.
机译：黑升麻（Cimicifuga racemosa）最常用于治疗更年期期间可能出现的症状。然而，在过去的几年中，人们已经对其安全性提出了一些担忧。该系统评价的目的是评估黑升麻安全性的临床证据。在5个计算机数据库（Medline，Embase，Amed，Phytobase和Cochrane库）中进行了系统的文献检索。扫描所有找到的文章的参考文献以查找其他相关出版物。考虑了包括病例报告和观察性研究在内的任何类型的临床数据。没有语言限制。确定了13项临床试验（所有这些均表明相对安全），3项上市后监测研究，4例病例系列报告和8例单例报告。临床研究表明，黑升麻是安全的。在大多数情况下，因果归因是有问题的。总之，黑升麻与严重的安全隐患相关，迫切需要进一步调查。

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