How much platinum passes the placental barrier? Analysis of platinum applications in 21 patients with cervical cancer during pregnancy

Koehler Christhardt; Oppelt Peter; Favero Giovanni; Morgenstern Bernd; Runnebaum Ingo; Tsunoda Audrey; Schmittel Alexander; Schneider Achim; Mueller Michael; Marnitz Simone

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How much platinum passes the placental barrier? Analysis of platinum applications in 21 patients with cervical cancer during pregnancy

机译：多少铂金穿过胎盘屏障？妊娠期21例宫颈癌患者铂类药物应用分析

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OBJECTIVE: Cervical cancer is the most common solid cancer diagnosed in pregnancy. Platinum is an active drug in the treatment of patients with cervical cancer. In the second and third trimesters, platinum is used to prevent cancer progression until fetal maturity is reached. However, knowledge about the transplacental passage of platinum is very limited.

机译：目的：宫颈癌是妊娠期最常见的实体癌。铂是治疗宫颈癌患者的活性药物。在中期和中期，铂可用于预防癌症发展直至胎儿成熟。但是，关于铂经胎盘通过的知识非常有限。

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来源
《American Journal of Obstetrics and Gynecology》 |2015年第2期|共2页
作者
Koehler Christhardt; Oppelt Peter; Favero Giovanni; Morgenstern Bernd; Runnebaum Ingo; Tsunoda Audrey; Schmittel Alexander; Schneider Achim; Mueller Michael; Marnitz Simone;
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正文语种 eng
中图分类妇产科学;
关键词
cervical cancer; neoadjuvant chemotherapy; platinum concentration; pregnancy; transplacental transport;

机译：宫颈癌;新辅助化疗;铂浓度;妊娠;经胎盘转运;

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专利

1. How much platinum passes the placental barrier? Analysis of platinum applications in 21 patients with cervical cancer during pregnancy [J] . Koehler Christhardt, Oppelt Peter, Favero Giovanni, American Journal of Obstetrics and Gynecology . 2015,第2期

机译：多少铂金穿过胎盘屏障？妊娠期21例宫颈癌患者铂类药物应用分析
2. Platinum derivatives during pregnancy in cervical cancer: A systematic review and meta-analysis [J] . ZagouriF., SergentanisT.N., ChrysikosD., Obstetrics and Gynecology: Journal of the American College of Obstetricians and Gynecologists . 2013,第2aPta1期

机译：宫颈癌妊娠期间的铂衍生物：系统评价和荟萃分析
3. A Multi-Institutional Retrospective Analysis of Oncologic Outcomes for Chinese Patients with Locally Advanced Cervical Cancer Undergoing Platinum-Based Adjuvant Chemotherapy after Concurrent Chemoradiotherapy [J] . Cheng G., Wu N., Su X., International Journal of Radiation Oncology, Biology, Physics . 2018,第3Suppla期

机译：中国局部晚期宫颈癌患者肿瘤成果的多制度回顾性分析，经过铂族型辅助化疗后同步化疗疗法
4. Chapter 21 Platinum Nanoparticles with Adsorptive Layer of Chlorella vulgaris Polysaccharides Inactivate Tumor Cells of Ascitic Ehrlich Carcinoma, Ovarian Cancer and Leukemia [C] . V. R. Estrela-Llopis, A. V. Chevichalova, N. A. Tregubova, FP7 International Summer School "Nanotechnology: From Fundamental Research to Innovations" . 2015

机译：第21章铂族纳米粒子与小球藻的吸附层，不含多糖杀死肠癌癌，卵巢癌和白血病的肿瘤细胞
5. Synthesis and characterization of novel platinum(II) and platinum(IV) complexes containing 4,4'-disubstituted-2,2'- bipyridine ligands for the treatment of cancer. [D] . Vo, Van. 2014

机译：含有4,4'-双取代-2,2'-联吡啶配体的新型铂（II）和铂（IV）配合物的合成和表征，用于治疗癌症。
6. Efficacy of neoadjuvant platinum-based chemotherapy during the second and third trimester of pregnancy in women with cervical cancer: an updated systematic review and meta-analysis [O] . Yizuo Song, Yi Liu, Min Lin, 2019

机译：宫颈癌女性在妊娠中期和妊娠中期新辅助铂类化学疗法的疗效：更新的系统评价和荟萃分析
7. Efficacy of neoadjuvant platinum-based chemotherapy during the second and third trimester of pregnancy in women with cervical cancer: an updated systematic review and meta-analysis [O] . Yizuo Song, Yi Liu, Min Lin, 2018

机译：新辅助铂化疗在宫颈癌妇女妊娠第二和第三三个三个月期间的疗效：更新的系统审查与荟萃分析

How much platinum passes the placental barrier? Analysis of platinum applications in 21 patients with cervical cancer during pregnancy

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