...
首页> 外文期刊>American Journal of Obstetrics and Gynecology >Effects of stress and depression on inflammatory immune parameters in pregnancy
【24h】

Effects of stress and depression on inflammatory immune parameters in pregnancy

机译:压力和抑郁对妊娠炎症性免疫指标的影响

获取原文
获取原文并翻译 | 示例
           

摘要

There is a substantial body of literature that links psychological stress to adverse pregnancy outcomes, particularly preterm birth. Comparatively few studies have examined potential biologic mechanisms that explain these associations. Attention to inflammatory processes is warranted. This article describes emerging studies that demonstrate that, as in nonpregnant humans and animals, psychological stress and distress (ie, depressive symptoms) predict dysregulation of inflammatory processes in human pregnancy. This includes elevations in circulating inflammatory cytokines, exaggerated inflammatory responses to in vivo biologic challenges, and more robust inflammatory responses to psychological challenges. Continued research in this area is needed to determine the implications of such stress-induced immune dysregulation for birth outcomes and for maternal health and fetal development.
机译:有大量文献将心理压力与不良妊娠结局(特别是早产)联系起来。相对较少的研究检查了解释这些关联的潜在生物学机制。必须注意炎症过程。本文介绍了新兴研究,这些研究表明,与未怀孕的人和动物一样,心理压力和困扰(即抑郁症状)预示着人类妊娠中炎症过程的失调。这包括循环炎症细胞因子的升高,对体内生物学挑战的过度炎症反应以及对心理挑战的更强烈的炎症反应。需要在这一领域继续研究以确定这种应激诱导的免疫失调对出生结局以及对孕产妇健康和胎儿发育的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号