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首页> 外文期刊>American journal of primatology >Identification of Helicobacter sp in gastric mucosa from captive marmosets (Callithrix sp.; Callitrichidae, primates)
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Identification of Helicobacter sp in gastric mucosa from captive marmosets (Callithrix sp.; Callitrichidae, primates)

机译:从圈养mar猴中鉴定胃粘膜中的幽门螺杆菌(Callithrix sp。; Callitrichidae,灵长类)

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摘要

The aim of this study was to identify the presence of Helicobacter sp. in the gastric mucosa of captive marmosets (Callithrix sp.). Histologic specimens from the fundic, corpus, and antral gastric regions of six Callithrix jacchus, 12 C. kuhli, and 12 C. geoffroyi specimens were evaluated. The sections were stained with hematoxylin-eosin (H&E) and the Warthin-Starry silver impregnation method, and immunostained with rabbit anti-H. pylori polyclonal antibody. Helicobacter-like organisms (HLOs) and coccoid forms were present in silver-stained sections from 29 stomachs, whereas immunohistochemistry (IHC) tests revealed bacterial aggregates in 15 stomachs. No statistical difference relative to the presence of Helicobacter sp. was found among the gastric regions or marmoset species. Gastric lesions were found in the groups of marmosets that had positive and negative IHC results, but no correlation between inflammation and Helicobacter sp. infection was established. These findings demonstrate that marmosets are susceptible to naturally-occurring Helicobacter sp. infection, and open the way to the development of comparative studies on Helicobacter sp. infection in humans. Am. J. Primatol. 66:111-118, 2005. (c) 2005 Wiley-Liss, Inc.
机译:这项研究的目的是确定幽门螺杆菌的存在。在圈养mar猴的胃粘膜中(Callithrix sp。)。评估了六个Callithrix jacchus,12 C. kuhli和12 C. geoffroyi标本的胃底,胃体和胃窦区域的组织学标本。切片用苏木精-曙红(H&E)和Warthin-Starry银浸渍法染色,并用兔抗H免疫染色。幽门螺杆菌多克隆抗体。在来自29个胃的银染切片中,存在类幽门螺杆菌(HLOs)和类球菌形式,而免疫组织化学(IHC)测试显示15个胃中有细菌聚集。相对于Helicobacter sp。的存在没有统计学差异。在胃区域或mar猴物种中发现。在IHC结果为阳性和阴性的mos猴组中发现了胃部病变,但炎症与Helicobacter sp之间没有相关性。确定感染。这些发现表明,mos猴容易感染自然存在的幽门螺杆菌。感染,为幽门螺杆菌的比较研究的发展开辟了道路。人类感染。上午。 J. Primatol。 66:111-118,2005.(c)2005 Wiley-Liss,Inc.

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