...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American journal of psychiatry >Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths.
【24h】

Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths.

机译：青年人严重的情绪失调，易怒和躁郁症的诊断范围。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In recent years, increasing numbers of children have been diagnosed with bipolar disorder. In some cases, children with unstable mood clearly meet current diagnostic criteria for bipolar disorder, and in others, the diagnosis is unclear. Severe mood dysregulation is a syndrome defined to capture the symptomatology of children whose diagnostic status with respect to bipolar disorder is uncertain, that is, those who have severe, nonepisodic irritability and the hyperarousal symptoms characteristic of mania but who lack the well-demarcated periods of elevated or irritable mood characteristic of bipolar disorder. Levels of impairment are comparable between youths with bipolar disorder and those with severe mood dysregulation. An emerging literature compares children with severe mood dysregulation and those with bipolar disorder in longitudinal course, family history, and pathophysiology. Longitudinal data in both clinical and community samples indicate that nonepisodic irritability in youths is common and is associated with an elevated risk for anxiety and unipolar depressive disorders, but not bipolar disorder, in adulthood. Data also suggest that youths with severe mood dysregulation have lower familial rates of bipolar disorder than do those with bipolar disorder. While youths in both patient groups have deficits in face emotion labeling and experience more frustration than do normally developing children, the brain mechanisms mediating these pathophysiologic abnormalities appear to differ between the two patient groups. No specific treatment for severe mood dysregulation currently exists, but verification of its identity as a syndrome distinct from bipolar disorder by further research should include treatment trials.
机译：近年来，越来越多的儿童被诊断出患有躁郁症。在某些情况下，情绪不稳定的儿童显然符合当前对躁郁症的诊断标准，而在其他情况下，诊断尚不清楚。严重的情绪失调是一种综合症，旨在捕获对双相情感障碍的诊断状态不确定的儿童的症状，即那些患有严重的，非周期性的易怒性和躁狂症的特征为高躁狂症状但缺乏明确界定的儿童的症状。躁郁症的情绪升高或易怒。躁郁症和严重情绪失调的年轻人之间的损伤程度相当。新兴文献在纵向过程，家族史和病理生理学方面比较了患有严重情绪失调的儿童和患有双相情感障碍的儿童。临床和社区样本中的纵向数据表明，青少年的非发作性烦躁是常见的，并且与成年期焦虑症和单相抑郁症（而非双相情感障碍）的风险升高有关。数据还表明，情绪严重失调的年轻人比双相情感障碍的家庭患双相情感障碍的比率更低。虽然这两个患者组的年轻人都比正常发育的儿童面部表情标签缺乏，并且经历了更多的挫折感，但是介导这些病理生理异常的大脑机制在两个患者组之间似乎有所不同。目前尚无针对严重情绪失调的具体治疗方法，但通过进一步研究证实其与双相情感障碍不同的综合征的身份应包括治疗试验。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号