...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Allergy >Important questions in Allergy: 1--drug allergy/hypersensitivity.
【24h】

Important questions in Allergy: 1--drug allergy/hypersensitivity.

机译：过敏的重要问题：1-药物过敏/超敏反应。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Drugs can induce several different types of immunological reactions which represent, together with nonallergic drug hypersensitivity reactions (DHRs), 15% of adverse drug reactions. Nonallergic DHRs resemble an allergy, without any proven immunological process. DHRs are a major cause of postmarketing withdrawal. They are also a daily worry for clinicians and patients. Even though urticarial and maculopapular eruptions are the most frequent manifestations, there are many other clinical forms, some of which are life-threatening, require or prolong hospital-ization and entail changes in the drug prescription (1) DHRs affect more than 7% of the general population and therefore represent an important public health problem (2) Both under-diagnosis [because of under-reporting (2, 3)] and over-diagnosis [because of the over-use of the term 'allergy' (2, 4)] are potential problems. Misclassification based on the drug allergy history may have consequences on individual treatment choices and can lead to the use of more expensive and less effective drugs.
机译：药物可以诱导几种不同类型的免疫反应，与非过敏性药物超敏反应（DHR）一起，占药物不良反应的15％。非过敏性DHR类似于过敏，没有任何经过验证的免疫过程。 DHR是上市后退出的主要原因。对于临床医生和患者来说，它们也是每天的烦恼。即使荨麻疹和斑丘疹喷发是最常见的表现，但还有许多其他临床形式，其中一些威胁生命，需要或延长住院时间，并需要改变药物处方（1）DHR影响了超过7％的人（2）诊断不足[由于报告不足（2，3）]和诊断过度[由于过度使用了“过敏”一词（2， 4）]是潜在的问题。基于药物过敏史的分类错误可能对个体治疗选择产生影响，并可能导致使用更昂贵和更无效的药物。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号