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首页> 外文期刊>Allergy >Severe anaphylaxis to the antiseptic polyhexanide.
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Severe anaphylaxis to the antiseptic polyhexanide.

机译:对防腐剂聚己二烯有严重的过敏反应。

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摘要

An 81-year-old female patient experienced symptoms of a grade III anaphylaxis with palmar oruritus. flush, swelling of the lips, swallowing difficulties, hypotension and loss of consciousness while using a new brand of wet toilet paper containing polyhexanide as disinfectant. The detailed allergy history revealed that the patient had experienced three similar anaphylactic episodes (grade II) during wound care of an existing leg ulcer, once when using a new wound dressing that contained polyhexanide (Suprasorb PHMB) and twice after wound cleansing with two different polyhexanide disinfectants (Lavanid 1 and Prontosan). The patient had no known allergies or atopic diseases. Total IgE was elevated (411 kU/l), there were no specific IgE detected for common seasonal and perennial inhalation allergens, base line mast cell tryptase was normal (3.07 mug/l). Skin prick tests (SPT) were positive for Lavanid 1 in a 1 : 10 dilution corresponding to 20 mug/ml polyhexanide. Except for polyethylene glycol (PEG) 4000, Lavanid 1 contains no other additives.
机译:一位81岁的女性患者出现手掌口臭的III级过敏反应症状。使用含有聚己二胺的新型湿厕纸作为消毒剂时,潮红,嘴唇肿胀,吞咽困难,低血压和意识丧失。详细的过敏史显示,该患者在对现有腿溃疡的伤口护理过程中经历了三个类似的过敏性发作(II级),一次是在使用含有聚己二酸(Suprasorb PHMB)的新伤口敷料时,两次是在用两种不同的聚己二酸清洗伤口后消毒剂(Lavanid 1和Prontosan)。该患者没有已知的过敏或特应性疾病。总IgE升高(411 kU / l),未发现常见的季节性和多年生吸入性过敏原的特异性IgE,基线肥大细胞类胰蛋白酶正常(3.07 cup / l)。 Lavanid 1的皮肤点刺试验(SPT)以1:10的稀释度呈阳性,对应于20杯/毫升的聚己酰胺。除聚乙二醇(PEG)4000外,Lavanid 1不包含其他添加剂。

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