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Surveillance of contact allergies: Methods and results of the Information Network of Departments of Dermatology (IVDK)

机译:接触过敏的监测:皮肤科信息网络(IVDK)的方法和结果

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摘要

Contact allergy (CA) surveillance networks provide information to a multitude of stakeholders, which is indispensable for evidence-based decision-making in the field of prevention. Methods and results of the German surveillance system on CA are reviewed and discussed with reference to other systems. The German network structure comprises 56 departments of dermatology and includes all patients who are patch-tested for suspected CA. Data analysis considers the results of patch testing and further pertinent information for each patient. Following aspects are addressed: (i) the description of the clinical population, (ii) evaluation of patch test reactions, (iii) relationship between patch test results and population characteristics. Trend analyses on chromate (decreasing), epoxy resin (increasing) and nickel (heterogeneous) served as examples for surveillance system analyses, with the identification of sentinel events, as well as proof of success or failure of prevention. In addition, external data sources can be used such as sales data of patch test preparations to estimate frequencies of sensitization on a population level. National prescription data of drugs and statistics of labelling of preservatives on cosmetics can be included, the latter two approaches allowing for risk estimates conferred by specific allergens.
机译:接触过敏(CA)监视网络为众多利益相关者提供信息,这对于预防领域中基于证据的决策是必不可少的。审查并讨论了德国CA监视系统的方法和结果,并参考了其他系统。德国的网络结构包括56个皮肤科,包括所有经过补丁测试的可疑CA患者。数据分析考虑了补丁测试的结果以及每个患者的其他相关信息。涉及以下方面:(i)临床人群的描述,(ii)斑贴试验反应的评估,(iii)斑贴试验结果与人群特征之间的关系。铬酸盐(减少),环氧树脂(增加)和镍(异质)的趋势分析可作为监视系统分析的示例,可以识别前哨事件,并可以证明预防的成败。此外,可以使用外部数据源(例如贴片测试制剂的销售数据)来估计总体上的敏化频率。可以包括药品的国家处方数据和化妆品上的防腐剂标签统计数据,后两种方法允许对特定变应原赋予的风险进行估算。

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