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EAACI position paper: Skin prick testing in the diagnosis of occupational type i allergies

机译：EAACI立场文件：皮肤点刺试验在职业性i型过敏的诊断中

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摘要

Skin prick testing (SPT) in combination with the clinical history of the patient is one important step in the diagnosis of IgE-mediated occupational allergies. However, skin test performance is related to the quality of allergen extracts. The present consensus document was prepared by an EAACI Task Force consisting of an expert panel of allergologists and occupational physicians from Germany, Italy, Spain, France, Austria, and Poland. All members of the panel were also involved in the data collection within the European multicentre study STADOCA (Standard diagnosis for occupational allergy). The aim of this Task Force was the assessment of the quality of commercially available SPT solutions for selected occupational allergens under standardized procedure conditions in different European centres and institutes of Occupational Medicine. The data evaluation shows a wide variability among SPT solutions and also indicates that the sensitivity of several SPT solutions is low. Therefore, improvement and standardization of SPT solutions for occupational allergens is highly recommended. Clinical practitioners should also not presume that their SPT solutions are fully reliable. The main objective of the document is to issue consensus suggestions for the use of SPT with occupational allergens based on the European multicentre study STADOCA, on existing scientific evidence and the expertise of a panel of allergologists.
机译：皮肤点刺试验（SPT）与患者的临床病历相结合是诊断IgE介导的职业过敏的重要一步。但是，皮肤测试性能与过敏原提取物的质量有关。本共识文件是由EAACI工作队准备的，该工作队由来自德国，意大利，西班牙，法国，奥地利和波兰的过敏症专家和职业医师组成的专家小组组成。小组的所有成员还参与了欧洲多中心研究STADOCA（职业过敏的标准诊断）中的数据收集。该工作队的目的是评估欧洲不同中心和职业医学研究所在标准程序条件下针对某些职业过敏原的市售SPT解决方案的质量。数据评估显示SPT解决方案之间存在很大差异，并且还表明几种SPT解决方案的灵敏度较低。因此，强烈建议对用于职业过敏原的SPT解决方案进行改进和标准化。临床医生也不应假定其SPT解决方案是完全可靠的。该文件的主要目的是在欧洲多中心研究STADOCA的基础上，根据现有科学证据和过敏学家小组的专业知识，就将SPT与职业性过敏原一起使用提出共识性建议。

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