...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Allergy >Natural evolution of skin-test sensitivity in patients with IgE-mediated hypersensitivity to cephalosporins
【24h】

Natural evolution of skin-test sensitivity in patients with IgE-mediated hypersensitivity to cephalosporins

机译：IgE介导的对头孢菌素超敏反应患者皮肤测试敏感性的自然演变

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There are studies demonstrating that skin-test sensitivity to penicillins can decrease over time and that allergic patients may lose sensitivity if the responsible compounds are avoided. With regard to subjects with IgE-mediated hypersensitivity to cephalosporins, however, such studies are lacking. We evaluated prospectively in a 5-year follow-up 72 cephalosporin-allergic patients. After the first evaluation, patients were classified into two groups according to their patterns of allergologic-test positivity: to both penicillins and cephalosporins (group A), or only to cephalosporins (group B). Skin tests and serum-specific IgE assays were repeated 1 year later and, in case of persistent positivity, 3 and 5 years after the first allergologic examination. Seven (43.7%) of the 16 subjects of group A and 38 (67.8%) of the 56 patients of group B became negative; one was lost to follow-up. Patients of group B became negative sooner and more frequently than group A subjects.
机译：有研究表明，皮肤试验对青霉素的敏感性会随着时间的流逝而降低，如果避免使用负责任的化合物，过敏性患者可能会失去敏感性。然而，关于IgE介导的对头孢菌素超敏反应的受试者，尚缺乏此类研究。我们在5年的随访中对72例头孢菌素过敏患者进行了前瞻性评估。第一次评估后，根据变应性试验阳性的方式将患者分为两组：青霉素和头孢菌素（A组），或仅头孢菌素（B组）。皮肤测试和血清特异性IgE测定在1年后重复进行，如果持续呈阳性，则在第一次变应性检查后3和5年重复进行。 A组16名受试者中有7名（43.7％）和B组56名患者中的38名（67.8％）变为阴性;一名失去了后续行动。 B组患者比A组受试者更快，更阴性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号