eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

Li X.; Hastie A. T.; Hawkins G. A.; Moore W. C.; Ampleford E. J.; Milosevic J.; Li H.; Busse W. W.; Erzurum S. C.; Kaminski N.; Wenzel S. E.; Meyers D. A.; Bleecker E. R.

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eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

机译：支气管上皮细胞的eQTL和支气管肺泡灌洗解密GWAS鉴定的哮喘基因

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Background: Genome-wide association studies (GWASs) have identified various genes associated with asthma, yet, causal genes or single nucleotide polymorphisms (SNPs) remain elusive. We sought to dissect functional genes/SNPs for asthma by combining expression quantitative trait loci (eQTLs) and GWASs.

机译：背景：全基因组关联研究（GWAS）已鉴定出与哮喘有关的各种基因，但因果基因或单核苷酸多态性（SNP）仍然难以捉摸。我们试图通过结合表达定量性状基因座（eQTLs）和GWASs来分析哮喘的功能基因/ SNP。

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《Allergy》 |2015年第10期|共10页
作者
Li X.; Hastie A. T.; Hawkins G. A.; Moore W. C.; Ampleford E. J.; Milosevic J.; Li H.; Busse W. W.; Erzurum S. C.; Kaminski N.; Wenzel S. E.; Meyers D. A.; Bleecker E. R.;
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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
asthma susceptibility genes; bronchial alveolar lavage; bronchial epithelial cells; eQTL; Genome-wide association studies;

机译：哮喘易感基因;支气管肺泡灌洗;支气管上皮细胞;eQTL;全基因组关联研究;

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专利

1. eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes [J] . Li X., Hastie A. T., Hawkins G. A., Allergy . 2015,第10期

机译：支气管上皮细胞的eQTL和支气管肺泡灌洗解密GWAS鉴定的哮喘基因
2. FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury [J] . Tingting Yuan, Thomas Volckaert, Elizabeth F. Redente, Stem Cell Reports . 2019,第5期

机译：FGF10-FGFR2B信号产生肺损伤后基底细胞并通过支气管上皮干细胞驱动肺泡上皮再生
3. In vitro adhesion and invasion by Cladosporium sphaerospermum in human bronchial epithelial cells (BEAS-2B) and human pulmonary alveolar epithelial cells (HPAEpiC) [J] . Lo S G, Wong S F, Mak J W, Tropical biomedicine. . 2019,第4期

机译：通过人支气管上皮细胞（BEA-2B）和人肺肺泡上皮细胞（HPAEPIC）的体外粘附和侵袭通过Cladosporium sphaerospermum
4. Detection of Chlamydia- Like Organisms in the Bronchial Alveolar Lavage from a SARS Patient [C] . . -1

机译：SARS患者支气管肺泡灌洗中衣原体样生物的检测
5. Line-1 Couples Epithelial-Mesenchymal Transition Programming with the Acquisition of Oncogenic Phenotypes in Human Bronchial Epithelial Cells [D] . Aispuro, Ivan O. 2020

机译：Line-1对上皮 - 间充质转换编程在人支气管上皮细胞中获取致癌表型
6. eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes [O] . Xingnan Li, Annette T. Hastie, Gregory A. Hawkins, -1

机译：支气管上皮细胞的eQTL和支气管肺泡灌洗解密GWAS鉴定的哮喘基因
7. FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury [O] . Tingting Yuan, Thomas Volckaert, Elizabeth F. Redente, 2019

机译：FGF10-FGFR2B信号传导产生基础细胞，并在肺损伤后支气管上皮干细胞驱动肺泡上皮再生

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

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