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Prevention of work-related airway allergies; summary of the advice from the Health Council of the Netherlands.

机译：预防与工作有关的气道过敏;荷兰卫生委员会的建议摘要。

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摘要

The Health Council of the Netherlands published a report in which the best procedure and method for recommending health-based occupational exposure limits (OELs) for inhaled allergens were identified by evaluating the scientific state of the art. Many respiratory disorders in the workplace arise from inhalation of substances which can cause allergy. To protect workers against respiratory allergy, various preventive measures are taken, one of them being reduction of exposure by setting legally binding standards. These are based on health-based OELs that specify a level of exposure to an airborne substance, a threshold level, below which it may reasonably be expected that there is no risk of adverse health effects. The Council is of the opinion that an OEL should prevent against allergic sensitization, as sensitization plays a crucial biological role and is a prerequisite for the development of allergy. Furthermore, the Council considers it most likely that the exposure level below which no allergic sensitization develops for most allergens is so low, that OELs are difficult to set with the current knowledge and technical feasibilities. An alternative approach is to accept exposure, which carries a small predefined risk in developing allergic sensitization. In addition, it is worth considering periodic screening of exposed workers on allergic sensitization, because timely intervention can prevent worse. The feasibility of periodic screening and what else is needed to comply with the most important criteria, should however be judged case-by-case.
机译：荷兰卫生理事会发表了一份报告，其中通过评估科学的技术水平，确定了推荐基于健康的吸入性过敏原职业接触限值（OEL）的最佳程序和方法。吸入许多可引起过敏的物质，导致工作场所出现许多呼吸系统疾病。为了保护工人免受呼吸道过敏，采取了多种预防措施，其中之一是通过制定具有法律约束力的标准来减少接触。这些是基于健康的OEL，这些OEL规定了空气传播物质的暴露水平，即阈值水平，可以合理地预期该水平以下不会对健康造成不利影响。理事会认为，OEL应防止过敏性致敏，因为致敏作用起着至关重要的生物学作用，是发生过敏的前提。此外，理事会认为最有可能的是，对于大多数过敏原而言，没有达到过敏致敏性的暴露水平如此之低，以致目前的知识和技术可行性难以确定OEL。另一种替代方法是接受暴露，这种暴露在产生过敏性致敏时具有较小的预定义风险。此外，值得考虑的是定期对接触过的工人进行过敏敏化检查，因为及时干预可以防止病情恶化。但是，应根据具体情况判断定期筛查的可行性以及满足最重要标准所需要采取的其他措施。

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