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首页> 外文期刊>感染症学雑誌 >Two cases of meningitis caused by the same Haemophilus influenzae type B strain in a nursery at a 3-month interval
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Two cases of meningitis caused by the same Haemophilus influenzae type B strain in a nursery at a 3-month interval

机译：两种脑膜炎患者由3个月间隔的幼儿园中相同的嗜血杆菌菌株B株

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摘要

We present 2 cases of meningitis caused by the same Haemophilus influenzae type b (Hib) strain in a nursery at a 3-month interval. Causative agents isolated showed good susceptibility to beta-lactams and both patients recovered without any sequelae. Survey culture at each occurrence of meningitis showed 10 asymptomatic nasopharyngeal carriers. Oral rifampin was administrated to all staff and infants, but 2 carriers were found a month later from chemoprophylaxis. Pulsed-field gel electrophoresis analysis showed that the two strains isolated from meningitis patients and 12 from asymptomatic carriers were apparently identical. When systemic Hib infection occurs in a nursery, other infants may be at high risk for secondary disease. It is difficult, however, to eliminate Hib carriage by chemoprophylaxis, indicating that Hib vaccination to prevent systemic Hib infection is necessary in Japan.
机译：我们在3个月间隔内呈现由苗圃中相同血液嗜血杆菌型B（HIB）菌株引起的脑膜炎病例。 分离的致病剂显示出对β-内酰胺的良好敏感性，并且两种患者都在没有任何后遗症的情况下恢复。 每次发生脑膜炎的调查文化显示出10种无症状的鼻咽携带者。 口服利福平被施用于所有员工和婴儿，但从化学普罗基斯毕发现了2个月的2个携带者。 脉冲场凝胶电泳分析表明，从脑膜炎患者和来自无症状载体中的12个菌株显然是相同的。 当托儿所发生全身性血管感染时，其他婴儿可能处于高等疾病的高风险。 然而，难以通过化学丙基脱落，表明日本是必要的，表明在日本是必要的血管疫苗接种疫苗接种。

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