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Pneumonia associated with lung cancer in the elderly

机译:肺炎与老年人肺癌有关

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We investigated the clinical characteristics separating pneumonia as a complication in elderly lung cancer patients into obstructive and non-obstructive pneumonia. Two hundred and five patients with pneumonia as a complication in elderly lung cancer patients were classified into two groups; 64 patients with obstructive pneumonia and 141 patients with non-obstructive pneumonia. Most of the patients in both groups were male. Concerning histological findings, while most of the patients with obstructive pneumonia had squamous cell carcinoma, those with non-obstructive pneumonia had the same proportion of squamous cell carcinoma as all elderly patients with lung cancer. Most of the patients with obstructive pneumonia were in good general condition including their nutritional condition, but the patients with non-obstructive pneumonia were in significantly poor condition. A low percent of microorganisms were isolated from the sputum obtained from the patients with non-obstructive pneumonia, but a high percentage were obtained from those with non-obstructive pneumonia. Frequent involvement of gram-negative bacilli such as Pseudomonas aeruginosa and Klebsiella pneumoniae or Staphylococcus aureus containing MRSA was also found in these patients. Regarding treatment, although carbapenem was used either alone or in combination therapy as the regimen of treatment for pneumonia as a complication in elderly lung cancer patients with both the obstructive and non-obstructive pneumonia patients, the efficacy rate was poor in 50% with obstructive pneumonia and in 26% with non-obstructive pneumonia. The mortality rate was 11% in the patients with obstructive pneumonia, while it was 61% in the patients with non-obstructive pneumonia. The prognosis was significantly poorer in the patients with non-obstructive pneumonia. We concluded that although the prognosis was not so poor for patients with obstructive pneumonia if the appropriate treatment was given, in the patients with non-obstructive pneumonia, the treatment for underlying diseases and the improvement of their general condition, including the determination of causative microorganisms, was important.
机译:我们调查了将肺炎患者作为老年肺癌患者的并发症分离为阻塞性和非阻塞性肺炎的临床特征。两百五名患有老年肺癌患者并发症的肺炎患者分为两组; 64例阻塞性肺炎患者和141例非阻塞性肺炎患者。两组的大多数患者都是男性。关于组织学结果,而大多数患有肺炎肺炎的患者具有鳞状细胞癌,那些患有非阻塞性肺炎的人与肺癌所有老年患者的鳞状细胞癌比例相同。大多数患有阻塞性肺炎的患者都处于良好的一般条件,包括它们的营养状况,但患有非阻塞性肺炎的患者病症明显差。从非阻塞性肺炎患者获得的痰液中分离出低百分之一的微生物,但是从具有非阻塞性肺炎的患者获得高百分比。在这些患者中还发现了克鲁氏阴性杆菌如假单胞菌铜绿假单胞菌和Klebsiella肺炎金黄色葡萄球菌的频繁参与。关于治疗,虽然CarbapeNem是单独使用的,或者在组合治疗中使用作为肺炎治疗的治疗方案作为老年肺癌患者对梗阻性和非阻塞性肺炎患者的并发症,但随着阻塞性肺炎的50%的疗效率差含有非阻塞性肺炎的26%。患有阻塞性肺炎患者的死亡率为11%,而非阻塞性肺炎的患者患有61%。非阻塞性肺炎患者的预后显着较差。我们得出结论,如果给予适当治疗的肺炎患者,患者在非阻塞性肺炎患者中,患者的患者,虽然对患者的患者,但潜在的疾病治疗以及其一般病症的改善,但包括致病性微生物的患者,虽然预后并不那么差。 ,很重要。

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