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首页> 外文期刊>感染症学雑誌 >G群に凝集するStreptococcus dysgalactiae subsp.equisimilisによる劇症型溶血レンサ球菌感染症の1例
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G群に凝集するStreptococcus dysgalactiae subsp.equisimilisによる劇症型溶血レンサ球菌感染症の1例

机译：Streptococcus Dysgalactiae Subsp.equisimilis的最终孵化肾素感染性疾病的情况，对G组进行粘聚

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摘要

Group G streptococcus (GGS) is infrequently associated with severe invasive soft tissue infection and toxic shock syndrome. A 74-year-old woman with a history of lymphedema of the lower extremities after surgical and radiation therapy for uterine cancer and diabetic mellitus and admitted for swelling of the right leg, fever, and dyspnea. She presented with shock and necrotizing cellulitis of the right lower extremity. Laboratory tests showed leukocytepenia, acute renal and liver dysfunction, and muscle damage. She rapidly developed multiple organ failure and necrotizing cellulitis. A swab from skin vesicle, throat, and blood culture grew Group G Streptococcus dysgalactiae subsp. equisimilis. Despite endotoxin hemoadsorption therapy, administration of antibiotics, and intravenous immunoglobulin, she died 9 days after admission due to toxic shock syndrome caused by GGS. The M-protein gene (emm) typing of GGS isolated from both blood and skin lesion showed stG 485.0. Three virulence genes, sagA, slo and skcg, were detected from GGS isolated from them.
机译：G组链球菌（GGS）不经常与严重的侵袭性软组织感染和毒性休克综合征相关。一名74岁的女性，具有下肢的淋巴水肿历史，后肢癌症和糖尿病患者的放射治疗，并承认右腿，发热和呼吸困难的肿胀。她患有震动和坏死性蜂窝织炎的右下肢。实验室试验显示白细胞，急性肾和肝功能障碍和肌肉损伤。她迅速发展了多种器官衰竭和坏死性蜂窝织炎。来自皮肤囊泡，喉咙和血液培养的拭子GROPS GREXTOCOCCCCOS DYSGALACTIAE SUBSP。 Equisimilis。尽管内毒素血液吸附治疗，抗生素和静脉注射免疫球蛋白，她在入院后9天死于GGS引起的毒性休克综合征。从血液和皮肤病变中分离的M蛋白基因（EMM）键入GGS显示STG 485.0。从与它们隔离的GGS检测到三种毒力基因，佐贺，SLO和SKCG。

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