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Influenza C virus isolated in Hiroshima Prefecture during the 1999/2000 winter season--a clinical and epidemiological study

机译:1999 / 2,000冬季在广岛县中孤立的流感C病毒 - 临床和流行病学研究

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摘要

Influenza C virus (Inf. C) is one of pathogens of human respiratory tract infection and prevalent throughout the world at an early stage in life. However, Inf. C has been isolated only accidentally and there have been few reports on its clinical and epidemiological features. From November 1999 to March 2000, Inf. C was isolated from clinical specimens (throat swabs) of 4 pediataric patients with respiratory tract illness at Hiroshima Prefectural Hospital and was isolated in 4 peditaric patients at the other medical institutions in Hiroshima prefecture. There were no differences in clinical features including duration of illness, duration of fever, maximum body temperature between 4 patients with Inf. C infection and patients with influenza A (H1N1 and H3N2) and influenza B infection from 1992 to 2000. We investigated geographical distribution of patients with inf. C infection and analyzed for antigenic characteristics with a set of monoclonal antibodies against hemagglutinin-esterase glycoproteins. Thedata suggested that at least two antigenically different Inf. C prevalented in a region during winter from 1999 to 2000.
机译:流感C病毒(INF。c)是人类呼吸道感染的病原体之一,在生活中的早期阶段。但是,INF。 C已被意外分离,并有很少有关于其临床和流行病学特征的报道。从1999年11月到2000年3月,INF。 C从广岛县医院呼吸道疾病的临床标本(喉拭子)中分离出来,在广岛县的其他医疗机构中分离出4名妇女患者。临床特征没有差异,包括疾病持续时间,发烧持续时间,4例患有4例患者的最大体温。 C感染和患有流感A(H1N1和H3N2)的患者(H1N1和H3N2)和1992年至2000年的流感B感染。我们调查了INF患者的地理分布。 C感染并分析了血凝素 - 酯酶糖蛋白的一组单克隆抗体的抗原特征。 Thedata建议至少两个抗原不同的inf。 C冬季从1999年到2000年的一个地区流入。

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