...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>臨床病理 >Prognosis of chronic hepatitis C with regard to the aim of treatment
【24h】

Prognosis of chronic hepatitis C with regard to the aim of treatment

机译：慢性丙型肝炎关于治疗目的的预后

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Epidemiology of hepatitis C virus(HCV) infection and clinical prognosis of chronic hepatitis C were presented here to reveal the object of treatment of Chronic Hepatitis C. Hepatitis C Virus is transmitted by blood and blood products. After acute HCV infection, about 70% developed persistent HCV infection, and the diagnosis is by finding viral RNA in the serum of patients with anti-HCV antibody. Persistent HCV infection causes chronic hepatitis, in which the natural clearance of HCV is almost impossible and there is almost no natural cure for chronic hepatitis caused by HCV. Chronic hepatitis C tends to develop gradually and to progress to liver cirrhosis, and is involved in the pathogenesis of hepatocellular carcinoma. In Japanese patients with chronic hepatitis C, 45% developed liver cirrhosis pass through a phase of chronic active hepatitis over a 15-year course after initial HCV infection, and 25% developed hepatocellular carcinoma over a 20-year course after the initial HCV infection. In addition the remaining patients may start to develop rapidly to chronic active hepatitis and to liver cirrhosis after 20 to 30 years duration of inactive phase. Thus, this type of chronic hepatitis reveals a poor long-term prognosis. For etiological treatment of chronic hepatitis C, eradication of persistent HCV infection is needed. If this is impossible, then preventing the development of liver cirrhosis and hepatocellular carcinoma is important.
机译：鉴于丙型肝炎病毒（HCV）感染和临床预后的流行病学介绍了慢性丙型肝炎的临床预后，揭示了慢性丙型肝炎的治疗对象。丙型肝炎病毒通过血液和血液制品传播。在急性HCV感染后，大约70％发育持久的HCV感染，并且诊断是通过在抗HCV抗体患者的血清中找到病毒RNA。持续的HCV感染导致慢性肝炎，其中HCV的自然清除几乎是不可能的，并且几乎没有对HCV引起的慢性肝炎的天然固化。慢性丙型肝炎倾向于逐渐发展并进入肝硬化，并参与肝细胞癌的发病机制。在日本患有慢性丙型肝炎患者的慢性丙型肝炎患者中，肝硬化45％在初始HCV感染后通过15年期慢性活性丙型肝炎的阶段通过，25％在初始HCV感染后的20年内发育肝细胞癌。此外，其余患者可能开始迅速发展到慢性活性肝炎和肝硬化后20至30年的无活性阶段。因此，这种类型的慢性肝炎揭示了较差的长期预后。对于慢性丙型肝炎的病因治疗，需要消除持续的HCV感染。如果这是不可能的，那么防止肝硬化和肝细胞癌的发展是重要的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号