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首页> 外文期刊>ACS applied materials & interfaces >Nanoporous Polymeric Nanofibers Based on Selectively Etched PS-b-PDIVIS Block Copolymers
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Nanoporous Polymeric Nanofibers Based on Selectively Etched PS-b-PDIVIS Block Copolymers

机译：基于选择性蚀刻的PS-b-PDIVIS嵌段共聚物的纳米多孔聚合物纳米纤维

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One-dimensional nanoporous polymeric nanofibers have been fabricated within an anodic aluminum oxide (AAO) membrane by a facile approach based on selective etching of poly(dimethylsiIoxane) (PDMS) domains in polystyrene-block-poly(dimethylsiloxane) (PS-b-PDMS) block copolymers that had been formed within the AAO template. It was observed that prior to etching, the well-ordered PS-b-PDMS nanofibers are solid and do not have any porosity. The postetched PS nanofibers, on the other hand, had a highly porous structure having about 20-50 nm pore size. The nanoporous polymeric fibers were also employed as a drug carrier for the native, continuous, and pulsatile drug release using Rhodamine B (RB) as a model drug. These studies showed that enhanced drug release and tunable drug dosage can be achieved by using ultrasound irradiation.
机译：一维纳米多孔聚合物纳米纤维已经通过在聚苯乙烯嵌段聚二甲基硅氧烷（PS-b-PDMS）中对聚二甲基硅氧烷（PDMS）域进行选择性刻蚀的简便方法，在阳极氧化铝（AAO）膜中制成。 ）已在AAO模板中形成的嵌段共聚物。观察到，在蚀刻之前，排列良好的PS-b-PDMS纳米纤维是固体，没有任何孔隙。另一方面，后蚀刻的PS纳米纤维具有高度多孔的结构，其孔径约为20-50 nm。纳米多孔聚合物纤维还被用作药物载体，使用罗丹明B（RB）作为模型药物来进行天然，连续和搏动性药物释放。这些研究表明，通过使用超声辐射可以提高药物释放和可调剂量。

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