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首页> 外文期刊>Allergy & clinical immunology international: official organ of the International Association of Allergology and Clinical Immunology >Unmet Needs in Urticaria
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Unmet Needs in Urticaria

机译：荨麻疹的需求未得到满足

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摘要

According to guidelines published by the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA~2LEN), and the European Dermatology Forum (EDF) [1], urticaria is characterized by the rapid appearance of wheals and/or angioedema. A wheal consists of three typical features: A central swelling of variable size almost invariably surrounded by a reflex erythema, associated itching or sometimes burning sensations, and a fleeting nature, with the skin returning to its normal appearance, usually within 1-24 h. Angioedema is characterized by sudden, pronounced swelling of the lower dermis and subcutis, sometimes associated with pain rather than itching. Although angioedema can occur anywhere on the body, frequently the eyelids, lips, and genitalia are involved but sometimes also the tongue and laryngo-pharynx, which can be life-threatening. Resolution can take up to 3 days. Two main types are subclassified, C1 inhibitor-deficient and non-C1 inhibitor-deficient angioedema [2].
机译：根据欧洲变态反应和临床免疫学会（EAACI），全球变态反应和哮喘欧洲网络（GA〜2LEN）和欧洲皮肤病学论坛（EDF）[1]发布的指南，荨麻疹的特征是迅速出现鲸和/或血管性水肿。鲸鱼具有三个典型特征：大小不一的中央肿胀，几乎总是被反射性红斑围绕，伴有瘙痒或有时灼热感，并且短暂，皮肤通常在1至24小时内恢复正常外观。血管性水肿的特征是下真皮和皮下组织突然明显肿胀，有时伴有疼痛而不是瘙痒。尽管血管性水肿可发生在身体的任何地方，但经常累及眼睑，嘴唇和生殖器，但有时还会累及可能危及生命的舌头和咽喉。解决方案最多可能需要3天。分为两种主要类型，C1抑制剂缺乏和非C1抑制剂缺乏血管性水肿[2]。

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