首页> 外文期刊>American Journal of Physiology >Role of plasma ANG II in the excretion of acute sodium load in a bird with salt glands (Anas platyrhynchos).
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Role of plasma ANG II in the excretion of acute sodium load in a bird with salt glands (Anas platyrhynchos).

机译:血浆ANG II在带盐腺的鸟(Anas platyrhynchos)的急性钠负荷排泄中的作用。

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摘要

This study was designed to further examine the role of plasma ANG II in the excretion of sodium in the Pekin duck, a bird with salt glands. Renal and extrarenal (salt gland) excretion of an intravenously administered isotonic saline load was monitored over a 4-h period in a group of eight birds under two conditions: the control condition, in which isotonic saline infusion decreased endogenous plasma ANG II from 102.6 to 16.5 pg/ml, and the experimental condition, in which ANG II suppression was prevented by intravenous infusion of a 3.5 ng. kg(-1). min(-1) dose of synthetic ANG II. ANG II infusion significantly decreased the total sodium excretion (by 15%), primarily via an inhibition of salt gland output. The results suggest that ANG II suppression facilitates the excretion of an administered sodium load in birds with salt glands.
机译:这项研究旨在进一步研究血浆ANG II在北京咸鸭(有盐腺)中钠排泄中的作用。在两个条件下,在八种鸟类的一组中,在4小时内监测静脉内给予等渗盐水负荷的肾脏和肾外(盐腺)排泄:对照条件,等渗盐水注入将内源性血浆ANG II从102.6降低至16.5 pg / ml,以及实验条件,其中静脉注射3.5 ng可防止ANG II抑制。千克(-1)。合成ANG II的最小剂量(-1)。 ANG II输注显着降低了总钠排泄量(降低了15%),主要是通过抑制盐腺输出。结果表明,ANG II抑制可促进盐腺鸟体内钠负荷的排泄。

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