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首页> 外文期刊>American Journal of Physiology >Effect of endurance training on coronary artery size and function in healthy men: an invasive followup study.
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Effect of endurance training on coronary artery size and function in healthy men: an invasive followup study.

机译：耐力训练对健康男性冠状动脉大小和功能的影响：一项侵入性随访研究。

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摘要

In eight healthy male volunteers (cardiologists; age 36 +/- 5 yr), bicycle spiroergometry, Doppler echocardiography, and quantitative coronary angiography with intracoronary Doppler measurements before and after completion of a physical endurance exercise program of >5 mo duration were performed. Maximum oxygen uptake increased from 46 +/- 6 to 54 +/- 5 ml x kg(-1) x min(-1) (P = 0.04), maximum ergometric workload changed from 3.8 +/- 0.3 to 4.4 +/- 0.3 W/kg (P = 0.001), and left ventricular mass index increased from 82 +/- 18 to 108 +/- 29 g/m(2) (P = 0.001). The right, left main, and left anterior descending coronary artery cross-sectional area increased significantly in response to exercise. Before versus at the end of the exercise program, flow-induced left anterior descending coronary artery cross-sectional area was 10.1 +/- 3.5 and 11.0 +/- 3.9 mm(2), respectively (P = 0.03), nitroglycerin-induced left coronary calibers increased significantly, and coronary flow velocity reserve changed from 3.8 +/- 0.8 to 4.5 +/- 0.7 (P = 0.001). Left coronary artery correlated significantly with ventricular mass and maximum oxygen uptake, and coronary flow velocity reserve was significantly associated with maximum workload.
机译：在完成≥5mo耐力锻炼计划的前后，对八名健康的男性志愿者（心脏病学家; 36 +/- 5岁）进行了自行车体能计，多普勒超声心动图和冠状动脉内多普勒定量冠状动脉造影。最大吸氧量从46 +/- 6增加到54 +/- 5 ml x kg（-1）x min（-1）（P = 0.04），最大测功负荷从3.8 +/- 0.3更改为4.4 +/- 0.3 W / kg（P = 0.001），左心室质量指数从82 +/- 18增加到108 +/- 29 g / m（2）（P = 0.001）。锻炼后，右，左主干和左前降支冠状动脉横截面积显着增加。在锻炼程序结束之前和结束时，血流诱导的左冠状动脉前降支截面积分别为10.1 +/- 3.5和11.0 +/- 3.9 mm（2）（P = 0.03），硝酸甘油诱导的左冠状动脉口径显着增加，冠状动脉血流储备量从3.8 +/- 0.8变为4.5 +/- 0.7（P = 0.001）。左冠状动脉与心室质量和最大摄氧量显着相关，冠状动脉流速储备与最大工作量显着相关。

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