Cutting-edge technology. III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system.

Schemann M; Michel K; Peters S; Bischoff SC; Neunlist M

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Cutting-edge technology. III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system.

机译：尖端技术。三，影像学和胃肠道：绘制人类肠神经系统图。

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Monitoring membrane potentials by multisite optical recording techniques using voltage-sensitive dyes is ideal for direct analysis of network signaling. We applied this technology to monitor fast and slow excitability changes in the enteric nervous system and in hundreds of neurons simultaneously at cellular and subcellular resolution. This imaging technique presents a powerful tool to study activity patterns in enteric pathways and to assess differential activation of nerves in the gut to a number of stimuli that modulate neuronal activity directly or through synaptic mechanisms. The optical mapping made it possible to record from tissues such as human enteric nerves, which were, until now, inaccessible by other techniques.

机译：使用电压敏感染料通过多站点光学记录技术监测膜电位非常适合直接分析网络信号。我们应用了这项技术，以细胞和亚细胞分辨率同时监测肠神经系统和数百个神经元中兴奋性变化的快慢。这项成像技术提供了一个强大的工具，可研究肠道途径中的活动模式并评估肠道中神经对多种直接或通过突触机制调节神经元活动的刺激的差异激活。光学映射使从诸如人类肠神经等组织进行记录成为可能，而到目前为止，其他技术尚无法实现这些组织。

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《American Journal of Physiology》 |2002年第6期|共7页
作者
Schemann M; Michel K; Peters S; Bischoff SC; Neunlist M;
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正文语种 eng
中图分类人体生理学;
关键词
Digestive System; Electrophysiology; Enteric Nervous System; Image Processing; Computer-Assisted; 消化系统; 电生理学; 肠神经系统; 图像处理; 计算机辅助;

机译：Digestive System;Electrophysiology;Enteric Nervous System;Image Processing;Computer-Assisted;消化系统;电生理学;肠神经系统;图像处理;计算机辅助;

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1. Cutting-edge technology. III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system. [J] . Schemann M, Michel K, Peters S, American Journal of Physiology . 2002,第6期

机译：尖端技术。三，影像学和胃肠道：绘制人类肠神经系统图。
2. Quantitation of cellular components of the enteric nervous system in the normal human gastrointestinal tract--report on behalf of the Gastro 2009 International Working Group. [J] . Knowles CH, Veress B, Kapur RP, Neurogastroenterology and motility . 2011,第2期

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3. Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells. [J] . Hudson DM, Curtis SB, Smith V American Journal of Physiology . 2010,第3aPta1期

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4. Reconstruction of Nuclear Images in Human Gastrointestinal Tract Using An Electronic Engineering-based Capsule [C] . Xueling Liang, Xiaolin Zheng, Wensheng Hou, 2007 IEEE/ICME INTERNATIONAL CONFERENCE ON COMPLEX MEDICAL ENGINEERING . 2007

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5. On alpha-synuclein In the Human Enteric Nervous System. [D] . Gray, Madison Tanner. 2014

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Cutting-edge technology. III. Imaging and the gastrointestinal tract: mapping the human enteric nervous system.

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