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Role of plasma osmolality in the delayed onset of thermal cutaneous vasodilation during exercise in humans.

机译:血浆渗透压在人类运动过程中热皮肤血管舒张延迟发作中的作用。

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To elucidate the role of increased plasma osmolality (Posmol), which occurs during exercise in the regulation of cutaneous vasodilation (CVD) during exercise, we determined the relationship between the change in esophageal temperature (DeltaTes) required to elicit CVD (DeltaTes threshold for CVD) and Posmol during light and moderate exercise (30 and 55% of peak oxygen consumption, respectively) and passive body heating. Then we compared the relationship with the data obtained in our previous study [A. Takamata, K. Nagashima, H. Nose, and T. Morimoto. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R197-R204, 1997], in which we determined the relationships during passive body heating following isotonic (0.9% NaCl) or hypertonic (2 or 3% NaCl) saline infusions in the same subjects. Posmol values at 5 min after the onset of exercise were 287.5 +/- 0.9 mosmol/kgH2O during light exercise and 293.0 +/- 1.2 mosmol/kgH2O during moderate exercise. Posmol just before passive body heating was 289.9 +/- 1.4 mosmol/kgH2O. The DeltaTes threshold for CVD was 0.09 +/- 0.05 degrees C during light exercise, 0.31 +/- 0. 09 degrees C during moderate exercise, and 0.10 +/- 0.05 degrees C during passive body heating. The relationship between the DeltaTes threshold for CVD and Posmol was shown to be on the same regression line both during exercise and during passive body heating with or without infusions [A. Takamata, K. Nagashima, H. Nose, and T. Morimoto. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R197-R204, 1997]. Our data suggest that the elevated body core temperature threshold for CVD during exercise could be the result of increased Posmol induced by exercise and is not due to reduced plasma volume or the intensity of the exercise itself.
机译:为了阐明运动过程中血浆渗透压升高(Posmol)在运动过程中调节皮肤血管舒张(CVD)中的作用,我们确定了引起CVD所需的食管温度变化(DeltaTes)之间的关系(CVD的DeltaTes阈值) )和轻度和中度运动(分别为峰值耗氧量的30%和55%)和被动加热身体时的Posmol。然后,我们将该关系与先前研究中获得的数据进行了比较[A. Takamata,K.Nagashima,H.Nose和T.Morimoto。上午。 J.生理学。 273(Regulatory Integrative Comp。Physiol。42):R197-R204,1997],其中我们确定了在相同受试者中等渗(0.9%NaCl)或高渗(2%或3%NaCl)盐水注入后被动体加热过程中的关系。运动开始后5分钟的Posmol值为轻度运动时为287.5 +/- 0.9 mosmol / kgH2O,中度运动时为293.0 +/- 1.2 mosmol / kgH2O。被动加热之前的Posmol为289.9 +/- 1.4 mosmol / kgH2O。轻度运动时CVD的DeltaTes阈值为0.09 +/- 0.05摄氏度,中度运动时的DeltaTes阈值为0.31 +/- 0. 09摄氏度,被动体加热时为0.10 +/- 0.05摄氏度。在运动期间以及在有或没有输注的被动体加热过程中,CVD的DeltaTes阈值与Posmol之间的关系都显示在同一回归线上[A. Takamata,K.Nagashima,H.Nose和T.Morimoto。上午。 J.生理学。 273(Regulatory Integrative Comp。Physiol。42):R197-R204,1997]。我们的数据表明,运动期间CVD的较高的身体核心温度阈值可能是运动引起的Posmol升高的结果,而不是由于血浆量减少或运动本身的强度降低。

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