...
首页> 外文期刊>ACS Macro Letters >Force-Extension for DNA in a Nanoslit: Mapping between the 3D and 2D Limits
【24h】

Force-Extension for DNA in a Nanoslit: Mapping between the 3D and 2D Limits

机译:纳米缝隙中DNA的力扩展:3D和2D极限之间的映射

获取原文
获取原文并翻译 | 示例
           

摘要

The force extension relation for a semiflexible polymer confined in a nanoslit is investigated. Both the effective correlation length and force extension relation change as the chain goes from 3D (large slit heights) to 2D (tight confinement). At low forces, correlations along the polymer give an effective dimensionality. The strong force limit can be interpolated with the weak force limit for two regimes: when confinement dominates over extensile force and vice versa. These interpolations give good agreement with simulations for all slit heights and forces. We thus generalize the Marko-Siggia force-extension relation for DNA and other semiflexible biopolymers in nanoconfinement.
机译:研究了限制在纳米缝隙中的半柔性聚合物的力扩展关系。当链从3D(大缝隙高度)变为2D(紧密约束)时,有效相关长度和力延伸关系都会改变。在较小的力下,沿聚合物的相关性给出有效的尺寸。在两种情况下,可以用强力极限与弱力极限进行内插:当约束力超过伸展力时,反之亦然。这些插值与所有缝隙高度和力的模拟都很好地吻合。因此,我们概括了纳米约束中DNA和其他半柔性生物聚合物的Marko-Siggia力-延伸关系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号