...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ACS Macro Letters >Postalkylation of a Common mPEG-b-PAGE Precursor to Produce Tunable Morphologies of Spheres, Filomicelles, Disks, and Polymersomes
【24h】

Postalkylation of a Common mPEG-b-PAGE Precursor to Produce Tunable Morphologies of Spheres, Filomicelles, Disks, and Polymersomes

机译：常见的mPEG-b-PAGE前体的后烷基化以产生球形，细线状，盘状和聚合物小体的可调形态

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The facile synthesis of biocompatible materials that self-assemble into nanostructures of well-defined morphology is of keen interest to the biomedical community. Herein, we report on the use of methoxypoly(ethylene glycol)-b-poly(allyl glycidyl ether) (mPEG-b-PAGE) as a platform to generate a series of copolymers derivatized with pendant alkyl chains via thiol-ene click chemistry. Depending on the nature of their hydrophobic block and method of preparation, these amphiphilic block copolymers self-assemble in aqueous solution to form aggregates with distinct and unique morphologies. Spheres, long filomicelles, rods, disks and polymersomes with confirmed biocompatibility were formed from this series of copolymers. These materials hold great promise for use in biomedical applications such as drug delivery.
机译：自组装为形态明确的纳米结构的生物相容性材料的简便合成，对生物医学界非常感兴趣。在这里，我们报道了使用甲氧基聚（乙二醇）-b-聚（烯丙基缩水甘油醚）（mPEG-b-PAGE）作为平台来生成一系列通过硫醇-烯点击化学法与侧链烷基衍生化的共聚物的平台。根据其疏水嵌段的性质和制备方法，这些两亲嵌段共聚物在水溶液中自组装以形成具有独特独特形态的聚集体。由该系列共聚物形成了具有生物相容性的球形，长丝状细胞，棒状，盘状和聚合物小体。这些材料有望用于生物医学应用，例如药物输送。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号