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Endocrine control of osmoregulation in teleost fish

机译:硬骨鱼渗透调节的内分泌控制

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As the primary link between environmental change and physiological response, the neuroendocrine system is a critical part of osmoregulatory adaptations. Cortisol has been viewed as 'the' seawater-adapting hormone in fish and prolactin as 'the' fresh water adapting hormone. Recent evidence indicates that the growth hormone/insulin-like growth factor I axis is also important in seawater adaptation in several teleosts of widely differing evolutionary lineages. In salmonids, growth hormone acts in synergy with cortisol to increase seawater tolerance, at least partly through the upregulation of gill cortisol receptors. Cortisol under some conditions may promote ion uptake and interacts with prolactin during acclimation to fresh water. The osmoregulatory actions of growth hormone and prolactin are antagonistic. In some species, thyroid hormones support the action of growth hormone and cortisol in promoting seawater acclimation. Although a broad generalization that holds for all teleosts is unlikely, our current understanding indicates that growth hormone promotes acclimation to seawater, prolactin promotes acclimation to fresh water, and cortisol interacts witch both of these hormones thus having a dual osmoregulatory function.
机译:作为环境变化和生理反应之间的主要联系,神经内分泌系统是渗透调节适应性的关键部分。皮质醇被视为鱼类中的“海水适应激素”,而催乳素则被视为“淡水适应激素”。最近的证据表明,生长激素/胰岛素样生长因子I轴在海水鱼类适应中也很重要,这些鱼类的硬骨鱼具有广泛不同的进化谱系。在鲑鱼中,生长激素与皮质醇协同作用,至少部分通过through腮皮质醇受体的上调来增加海水的耐受性。在适应新鲜水的过程中,某些条件下的皮质醇可能会促进离子吸收并与催乳素相互作用。生长激素和催乳激素的渗透调节作用是拮抗的。在某些物种中,甲状腺激素支持生长激素和皮质醇在促进海水适应中的作用。尽管不可能对所有硬骨鱼进行广泛的概括,但我们目前的理解表明,生长激素促进了海水的适应性,催乳素促进了淡水的适应性,皮质醇与这两种激素相互作用,因此具有双重渗透调节功能。

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