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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Laser peripheral iridotomy with and without iridoplasty for primary angle-closure glaucoma: 1-year results of a randomized pilot study.
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Laser peripheral iridotomy with and without iridoplasty for primary angle-closure glaucoma: 1-year results of a randomized pilot study.

机译：原发性闭角型青光眼伴或不伴虹膜成形术的激光周边虹膜切开术：一项随机试验研究的1年结果。

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PURPOSE: To compare the efficacy and safety of laser peripheral iridotomy with or without laser peripheral iridoplasty in the treatment of eyes with synechial primary angle-closure or primary angle-closure glaucoma. DESIGN: Randomized, controlled clinical trial. METHODS: Consecutive patients older than 40 years with synechial primary angle-closure or primary angle closure glaucoma were recruited. Eligible patients were randomized to 1 of 2 treatment options, iridotomy or iridotomy plus iridoplasty, and were followed up for 1 year. Main outcome measures were intraocular pressure (IOP), peripheral anterior synechiae, corneal endothelial cell count, and complications. RESULTS: Seventy-seven eyes (77 patients) were randomized to the iridotomy group, and 81 eyes (81 patients) were randomized to the iridotomy plus iridoplasty group. Sixty-one patients (79.2%) in the iridotomy and 65 patients (80.2%) from the iridotomy plus iridoplasty groups completed 1 year of follow-up. There were no significant differences between the groups in the baseline data. IOP was reduced from 24.66 +/- 13.76 mm Hg to 19.03 +/- 6.21 mm Hg in the iridotomy group (P < .001) and from 27.96 +/- 13.06 mm Hg to 20.45 +/- 7.26 mm Hg in the iridotomy plus iridoplasty group (P < .001). Extent of peripheral anterior synechiae was decreased by 1 more clock-hour after iridoplasty compared with that after iridotomy in the iridotomy plus iridoplasty group (P < .001). There was no significant difference in IOP, medications, need for surgery, or visual function between groups at the 1-year visit. CONCLUSIONS: In eyes with synechial primary angle-closure or primary angle-closure glaucoma, both iridotomy alone or combined with iridoplasty provide a significant and equivalent reduction in IOP. There is also a possible reduction in peripheral anterior synechiae, more so in the iridoplasty group.
机译：目的：比较有或没有激光周边虹膜成形术的激光周边虹膜切开术在治疗伴有关节原发性闭角型或原发性闭角型青光眼的疗效和安全性。设计：随机对照临床试验。方法：招募了40岁以上的连续性伴有原发性闭角型青光眼或原发性闭角型青光眼的患者。符合条件的患者被随机分配到2种治疗方案中的1种（虹膜切开术或虹膜切开术加虹膜成形术），并随访1年。主要的预后指标是眼压（IOP），周围前粘连，角膜内皮细胞计数和并发症。结果：77眼（77例）被随机分配到虹膜切开术组，81眼（81例）被随机分配到虹膜切开加虹膜成形术组。虹膜切开术和虹膜成形术组的虹膜切开术中有61例患者（79.2％）和虹膜切开术加虹膜成形术组的65例患者（80.2％）完成了1年的随访。基线数据各组之间无显着差异。虹膜切开术组眼压从24.66 +/- 13.76 mm Hg降低到19.03 +/- 6.21 mm Hg（P <.001），虹膜切开术组从27.96 +/- 13.06 mm Hg降低到20.45 +/- 7.26 mm Hg虹膜成形术组（P <.001）。与虹膜切开加虹膜成形术组中虹膜切开术后相比，虹膜成形术后外周前粘膜粘连程度降低了1个时钟小时（P <.001）。在1年的访问中，两组之间的IOP，药物，手术需要或视觉功能之间无显着差异。结论：在患有关节原发性闭角型青光眼或原发性闭角型青光眼的眼中，单独虹膜切开术或虹膜成形术联合虹膜切开术均可以显着降低眼压。虹膜成形术组外周前粘膜粘连也可能减少。

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