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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Central corneal thickness in Northwestern American Indians/Alaskan Natives and comparison with White and African-American persons.
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Central corneal thickness in Northwestern American Indians/Alaskan Natives and comparison with White and African-American persons.

机译：西北美洲印第安人/阿拉斯加土著人的角膜中央厚度，并与白人和非裔美国人进行比较。

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摘要

PURPOSE: To determine the demographic factors associated with central corneal thickness (CCT) in Northwestern American Indians/Alaskan Natives (AI/ANs) and to compare these CCT measurements with those of White and African-American persons. DESIGN: Cross-sectional comparative, observational study. METHODS: We performed ultrasonic pachymetry (DGH-500 Pachette; DGH Technologies, Exton, Pennsylvania, USA) on a random sample of AI/AN subjects from three randomly selected AI/AN tribes in the Northwest United States (n = 429). Pachymetry also was performed on a convenience sample of White (n = 46) and African-American (n = 33) persons. Our main outcome measure was the average of right and left eye CCT. RESULTS: Average AI/AN CCT was 554.8 +/- 33.9 microm. AI/AN CCT was found to be thicker than that of African Americans (528.5 +/- 33.2 microm) but similar to that of White persons (551.9 +/- 28.3 microm). CCT was greater in AI/AN females than in AI/AN males (557.6 +/- 33.3 microm vs 550.1 +/- 34.5 microm; P = .03). We found no difference in CCT based on percent AI/AN heritage, age, and keratometry readings. We found no significant differences in mean CCT between AI/ANs with glaucoma (556.2 microm) and those who did not have glaucoma (556.6 microm). CONCLUSIONS: CCT measurements for the Northwest AI/AN population are similar to those of White persons but thicker than those of African-American persons. Although glaucoma is common in AI/ANs, we did not find an association with thin CCT. We need future studies to explore the risk factors for glaucoma in AI/ANs.
机译：目的：确定与西北印第安人/阿拉斯加土著人（AI / AN）的中央角膜厚度（CCT）相关的人口统计学因素，并将这些CCT测量值与白人和非裔美国人进行比较。设计：横断面比较观察研究。方法：我们对来自美国西北部三个随机选择的AI / AN部落（n = 429）的AI / AN受试者的随机样本进行了超声波测厚法（DGH-500 Pachette; DGH Technologies，Exton，美国）。对白人（n = 46）和非裔美国人（n = 33）的便利性样本也进行了测厚法。我们的主要结局指标是右眼和左眼CCT的平均值。结果：平均AI / AN CCT为554.8 +/- 33.9微米。发现AI / AN CCT比非裔美国人（528.5 +/- 33.2微米）厚，但与白人（551.9 +/- 28.3微米）相似。 AI / AN女性的CCT高于AI / AN女性（557.6 +/- 33.3微米vs 550.1 +/- 34.5微米; P = .03）。根据AI / AN遗产百分比，年龄和角膜曲率读数，我们发现CCT没有差异。我们发现，患有青光眼的AI / AN（556.2微米）与没有青光眼的AI / AN（556.6微米）之间的平均CCT没有显着差异。结论：西北地区AI / AN人群的CCT测量值与白人相似，但比非裔美国人更厚。尽管青光眼在AI / AN中很常见，但我们并未发现与薄型CCT相关。我们需要进一步的研究来探讨AI / AN中青光眼的危险因素。

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