...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >The variation in optical coherence tomography-measured macular thickness in diabetic eyes without clinical macular edema.
【24h】

The variation in optical coherence tomography-measured macular thickness in diabetic eyes without clinical macular edema.

机译：无临床黄斑水肿的糖尿病眼睛中光学相干断层扫描测量的黄斑厚度的变化。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To determine the variation in optical coherence tomography (OCT)-measured macular thickness in diabetic eyes without clinical edema and to investigate factors that might influence variation in macular thickness. DESIGN: Retrospective, observational case series from a clinical practice. METHODS: Review of clinical charts and longitudinal OCT measurements of a consecutive series of 56 eyes of 56 patients with diabetes but no clinical macular edema. Measured variables include OCT central subfield mean thickness (CSMT), total macular volume (TMV), and logarithm of the minimum angle of resolution (logMAR) visual acuity. RESULTS: Over a median follow-up of 17 months, interquartile range (IQR) (9, 23), the median variation in CSMT was 18 microns, IQR (11, 31), and the median variation in TMV was 0.09 mm(3), IQR (0.06, 0.16). Variation in CSMT did not change significantly with increasing CSMT. Absolute, but not relative, variation in TMV increased with increasing baseline values (P = .0127 and P = .1538 for absolute variation and relative variation in TMV, respectively). The variation in CSMT and TMV did not vary with follow-up time and did not vary with age, gender, race, hypertension status, glycosylated hemoglobin, or retinopathy level. CONCLUSIONS: Variation in CSMT and TMV in diabetic eyes without DME over intervals up to 17 months is no greater than OCT measurement variability in eyes without and with DME. A change in the OCT-measured macular thickness greater than 10% of the baseline thickness is likely to represent a true change in the macular thickness and not OCT measurement variability, diurnal variation, or variability occurring over longer time scales.
机译：目的：确定没有临床水肿的糖尿病眼中光学相干断层扫描（OCT）测量的黄斑厚度的变化，并调查可能影响黄斑厚度变化的因素。设计：来自临床实践的回顾性观察病例系列。方法：回顾性分析了56例无临床黄斑水肿的56例糖尿病患者连续56眼的临床图表和纵向OCT测量值。测得的变量包括OCT中心子场平均厚度（CSMT），总黄斑体积（TMV）和最小分辨角（logMAR）视敏度的对数。结果：在平均随访17个月，四分位数间距（IQR）（9，23）的情况下，CSMT的中位数变异为18微米，IQR（11，31），TMV的中位数变异为0.09 mm（3） ），IQR（0.06，0.16）。随着CSMT的增加，CSMT的变化没有显着变化。 TMV的绝对而非绝对变化随基线值的增加而增加（TMV的绝对变化和相对变化分别为P = .0127和P = .1538）。 CSMT和TMV的变化不随随访时间而变化，也不随年龄，性别，种族，高血压状态，糖化血红蛋白或视网膜病变水平而变化。结论：在没有DME的情况下长达17个月的间隔中，没有DME的糖尿病眼CSMT和TMV的变化不大于没有DME和有DME的OCT测量变异性。 OCT测量的黄斑厚度的变化大于基线厚度的10％可能代表黄斑厚度的真实变化，而不是OCT测量的变化，昼夜变化或较长时间范围内发生的变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号