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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Intraocular pressure, central corneal thickness, and prevalence of open-angle glaucoma: the Los Angeles Latino Eye Study.
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Intraocular pressure, central corneal thickness, and prevalence of open-angle glaucoma: the Los Angeles Latino Eye Study.

机译：眼内压，中央角膜厚度和开角型青光眼的患病率：洛杉矶拉丁裔眼研究。

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摘要

PURPOSE: To examine the relationship between the prevalence of open-angle glaucoma (OAG) and intraocular pressure (IOP) and the impact of central corneal thickness (CCT) on this relationship. DESIGN: Population-based cross-sectional study. METHODS: The study cohort consisted of 5,970 participants from the Los Angeles Latino Eye Study (LALES) with no history of glaucoma treatment and with complete ophthalmic examination data. The relationship between the prevalence of OAG and IOP was contrasted across persons with CCT designated as thin, normal, or thick. RESULTS: Prevalence of OAG was exponentially related to IOP. When stratified by CCT, persons with thin CCT had a significantly higher prevalence of OAG than did those with normal or thick CCTs at all levels of IOP. Adjusting each IOP individually for CCT did not impact significantly the relationship between the prevalence of OAG and IOP. CONCLUSIONS: These findings suggest that adjusting for the impact of CCT on IOP by correction algorithms is not necessary in a population based assessment of glaucoma prevalence; CCT, however, is an important independent risk factor for the prevalence of OAG.
机译：目的：探讨开角型青光眼（OAG）和眼内压（IOP）的发生率以及中央角膜厚度（CCT）对此关系的影响。设计：基于人群的横断面研究。方法：该研究队列由5970名来自洛杉矶拉丁裔眼研究（LALES）的参与者组成，他们没有青光眼的治疗史，并且具有完整的眼科检查数据。在CCT被指定为瘦，正常或胖的人群中，OAG和IOP患病率之间的关系得到了对比。结果：OAG的患病率与眼压呈指数关系。当按CCT进行分层时，在所有IOP水平下，CCT薄的人OCC的患病率均比正常或厚CCT的人高。分别针对CCT调整每个IOP不会显着影响OAG与IOP患病率之间的关系。结论：这些发现表明，在以人群为基础的青光眼患病率评估中，不需要通过校正算法来调整CCT对眼压的影响。但是，CCT是OAG患病率的重要独立风险因素。

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