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首页> 外文期刊>American journal on intellectual and developmental disabilities: AJIDD >Behavioral phenotype of fragile X syndrome in adolescence and adulthood
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Behavioral phenotype of fragile X syndrome in adolescence and adulthood

机译：青春期和成年期脆性X综合征的行为表型

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摘要

The present study explored the behavioral profile of individuals with fragile X syndrome during adolescence and adulthood. Individuals with both fragile X syndrome and autism (n 5 30) were compared with (a) individuals diagnosed with fragile X syndrome (but not autism; n 5 106) and (b) individuals diagnosed with autism (but not fragile X syndrome; n 5 135) on measures of autism symptoms, adaptive functioning, behavior problems, and psychological symptoms. Results indicated that individuals dually diagnosed with fragile X syndrome and autism displayed greater communication and social reciprocity impairments than individuals with fragile X syndrome only. Individuals in the dually diagnosed group also exhibited higher levels of repetitive and challenging behaviors than either comparison group, suggesting a unique profile of vulnerability for those diagnosed with both fragile X syndrome and autism.
机译：本研究探讨了在青春期和成年期患有脆性X综合征的个体的行为特征。将患有脆性X综合征和自闭症的个体（n 5 30）与（a）被诊断为脆性X综合征（但不是自闭症的个体; n 5 106）和（b）被诊断为自闭症（但不是脆性X综合征的个体; n 5 135）关于自闭症症状，适应功能，行为问题和心理症状的测量。结果表明，双重诊断为脆性X综合征和自闭症的人比仅脆性X综合征的人表现出更大的沟通和社交互惠障碍。双重诊断组中的个体表现出比任何一个对照组更高的重复性和挑战性行为水平，这表明对于那些同时患有脆性X综合征和自闭症的人而言，其脆弱性具有独特的特征。

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