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首页> 外文期刊>American Journal of Orthodontics and Dentofacial Orthopedics >Assessing salivary biomarkers for analyzing orthodontic tooth movement
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Assessing salivary biomarkers for analyzing orthodontic tooth movement

机译：评估唾液生物标志物以分析正畸牙齿的运动

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摘要

We read with interest the article by Professor Florez-lVloreno et al in the January issue investigating salivary levels of sRANKL and OPG and their ratios during orthodontic tooth movement, in an effort to determine the possibility of using these as biomarkers for chair-side point-of-care testing. The authors based their methodology on the premise that, as the different mediators involved in alveolar bone remodeling are being continuously washed into saliva by gingival crevicular fluid, unstimulated whole saliva could be an easier alternative to gingival crevicular fluid sampling of isolated sites. Although it is not our intention to detract credit from the findings of their study, we would prefer to interpret their findings with caution in light of the following.
机译：我们感兴趣地阅读了Florez-lVloreno教授等在1月份刊上发表的文章，该文章研究了正畸牙齿移动过程中唾液中sRANKL和OPG的水平及其比率，以期确定将其用作椅旁部位生物标记的可能性。现场测试。作者基于以下前提：他们的方法是，由于牙槽骨液不断将涉及牙槽骨重塑的不同介体不断冲洗到唾液中，未刺激的全唾液可能是对孤立部位的牙龈沟液取样的一种更容易的选择。尽管我们无意从他们的研究结果中减损信誉，但我们希望根据以下情况谨慎地解释他们的发现。

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