Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis

VonKeudellG.; SanchorawalaV.; OHaraC.; C.SeldinD.; SloanJ.M.

首页> 外文期刊>Amyloid: the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis >Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis

【24h】

Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis

机译：同时显示κ限制的慢性淋巴细胞白血病和λ轻链AL淀粉样变性

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We report on a 58-year-old man who presented with simultaneous kappa-restricted chronic lymphocytic leukemia (CLL) and a lambda-restricted plasma cell dyscrasia causing AL amyloidosis involving the kidney and GI tract. While monoclonal immunoglobulins occasionally produced by CLL has previously been implicated in AL amyloidosis, this is the first case of AL amyloidosis resulting from a distinct plasma cell dyscrasia that is not clonally related to the concurrent CLL. Appropriate treatment depended on detailed pathologic diagnosis of both disease processes.

机译：我们报道了一个58岁的男子，他同时出现kappa限制的慢性淋巴细胞性白血病（CLL）和lambda限制的浆细胞发育异常，导致涉及肾脏和胃肠道的AL淀粉样变性。虽然以前偶尔由CLL产生的单克隆免疫球蛋白已与AL淀粉样变性有关，但这是由明显的浆细胞发育异常所引起的AL淀粉样变性的首例病例，该异常与并发CLL没有克隆关系。适当的治疗取决于两种疾病过程的详细病理诊断。

著录项

来源
《Amyloid: the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis》 |2014年第2期|共4页
作者
VonKeudellG.; SanchorawalaV.; OHaraC.; C.SeldinD.; SloanJ.M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词
AL amyloidosis; CLL; Plasma cell dyscrasia;

机译：AL淀粉样变性;CLL;白细胞异常;

相似文献

外文文献
中文文献
专利

1. Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis [J] . VonKeudellG., SanchorawalaV., OHaraC., Amyloid: the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis . 2014,第2期

机译：同时显示κ限制的慢性淋巴细胞白血病和λ轻链AL淀粉样变性
2. The origin of deletion 22q11 in chronic lymphocytic leukemia is related to the rearrangement of immunoglobulin lambda light chain locus [J] . MrazM., StanoKozubikK., PlevovaK., Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis . 2013,第7期

机译：慢性淋巴细胞白血病删除22q11的起源与免疫球蛋白λ轻链基因座的重排有关
3. A Novel Risk-Model to Predict Time to First Treatment (TTT) in Chronic Lymphocytic Leukemia Based on Heavy plus Light Chain Immunoparesis and Serum Free Light Chain Analysis: Results from the Israeli CLL Study Group [J] . Tadmor Tamar, Braester Andrei, Dally Najib, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：一种新的风险模型，以预测慢性淋巴细胞白血病的第一次治疗（TTT）的时间基于重型轻链免疫血清和血清自由轻链分析：以色列CLL研究组的结果
4. A SUPERVISED ANALYSIS OF GENE-EXPRESSION PROFILES OF PURIFIED CLONAL PLASMA CELLS FROM PATIENTS WITH SYSTEMIC LIGHT-CHAIN AMYLOIDOSIS (AL) WHO HAVE HIGH OR LOW LEVELS OF SERUM FREE LAMBDA LIGHT CHAINS [C] . R.L Comenzo, P Zhou, M Fleisher, International Symposium on Amyloidosis . 2008

机译：具有高或低水量血清λ轻链的全身轻链淀粉样蛋白症（AL）患者纯化克隆血浆细胞基因表达谱的监督分析
5. Risk Factors for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Incidence in Postmenopausal Women: A Women's Health Initiative (WHI) Study [D] . Maharry, Kati S. 2016

机译：绝经后妇女慢性淋巴细胞白血病和小淋巴细胞淋巴瘤发生率的危险因素：妇女健康倡议（WHI）研究
6. Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda). [O] . A Solomon, B Frangione, E C Franklin 2013

机译：Bence Jones蛋白和免疫球蛋白轻链。人轻链的V lambda VI亚组与淀粉样变性AL（lambda）的优先关联。
7. Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia. [O] . Adachi, M, Cossman, J, Longo, D, 1989

机译：在慢性淋巴细胞性白血病中，bcl-2基因向免疫球蛋白λ轻链基因的变异易位。

Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis

摘要

著录项

相似文献

相关主题

期刊订阅