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首页> 外文期刊>Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland >Pulse pressure variation to predict fluid responsiveness in spontaneously breathing patients: Tidal vs forced inspiratory breathing
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Pulse pressure variation to predict fluid responsiveness in spontaneously breathing patients: Tidal vs forced inspiratory breathing

机译:脉冲压力变化可预测自然呼吸患者的液体反应性:潮气与强制吸气呼吸

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摘要

We evaluated whether pulse pressure variation can predict fluid responsiveness in spontaneously breathing patients. Fifty-nine elective thoracic surgical patients were studied before induction of general anaesthesia. After volume expansion with hydroxyethyl starch 6 ml.kg-1, patients were defined as responders by a ≥ 15% increase in the cardiac index. Haemodynamic variables were measured before and after volume expansion and pulse pressure variations were calculated during tidal breathing and during forced inspiratory breathing. Median (IQR [range]) pulse pressure variation during forced inspiratory breathing was significantly higher in responders (n = 29) than in non-responders (n = 30) before volume expansion (18.2 (IQR 14.7-18.2 [9.3-31.3])% vs 10.1 (IQR 8.3-12.6 [4.8-21.1])%, respectively, p 0.001). The receiver-operating characteristic curve revealed that pulse pressure variation during forced inspiratory breathing could predict fluid responsiveness (area under the curve 0.910, p 0.0001). Pulse pressure variation measured during forced inspiratory breathing can be used to guide fluid management in spontaneously breathing patients.
机译:我们评估了脉压变化是否可以预测自发性呼吸患者的液体反应性。在进行全身麻醉之前,对59名择期胸外科病人进行了研究。用6 ml.kg-1的羟乙基淀粉进行容量扩展后,将心脏指数增加≥15%定义为反应者。在潮气呼吸期间和强制吸气呼吸期间,测量体积膨胀前后的血流动力学变量,并计算脉压变化。容积扩大之前,响应者(n = 29)的强制吸气呼吸过程中的中压(IQR [范围])明显高于无反应者(n = 30)(18.2(IQR 14.7-18.2 [9.3-31.3])相对于10.1%(IQR 8.3-12.6 [4.8-21.1])%,p <0.001)。接收者操作特征曲线显示,在强制吸气呼吸过程中脉压变化可以预测流体反应性(曲线下面积0.910,p <0.0001)。强制吸气呼吸期间测得的脉压变化可用于指导自发呼吸患者的体液管理。

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