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首页> 外文期刊>American journal of industrial medicine >Urinary concentrations of trichloroacetic acid in Danish workers exposed to trichloroethylene, 1947-1985.
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Urinary concentrations of trichloroacetic acid in Danish workers exposed to trichloroethylene, 1947-1985.

机译:1947-1985年,丹麦三氯乙烯工人的尿中三氯乙酸浓度。

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摘要

BACKGROUND: Since 1947, the National Labour Inspection Service in Denmark has relied upon urinary measurements of trichloroacetic acid (TCA) in surveys of the occupational exposure to trichloroethylene (TCE). METHODS: We examined the paper files relating to 2397 TCA measurements to extract information about the year, the company, the work process and the worker. We used multiple regression models to analyze the effects of various factors on the urinary concentration of TCA. RESULTS: The regression analyses showed that (1) a four-fold decrease in TCA concentrations occurred from 1947 to 1985; (2) the highest concentrations were observed in the iron and metal, chemical, and dry cleaning industries; (3) TCA levels were two times higher among men compared with women in the iron and metal and dry cleaning industries; (4) TCA concentrations were higher among younger compared with older workers; and (5) persons working in an area in which TCE was used, but not working with TCE themselves, also showed urinary TCA levels indicative of exposure. CONCLUSIONS: Calendar year, type of industry, degree of contact with TCE, sex and age were predictors of TCA concentration in the urine of Danish workers.
机译:背景:自1947年以来,丹麦国家劳动监察局在对三氯乙烯(TCE)的职业暴露调查中一直依靠尿液中三氯乙酸(TCA)的测定。方法:我们检查了与2397个TCA测量有关的纸质文件,以提取有关年份,公司,工作过程和工人的信息。我们使用多元回归模型来分析各种因素对三氯乙酸尿浓度的影响。结果:回归分析表明:(1)TCA浓度从1947年到1985年下降了4倍。 (2)在钢铁,金属,化学和干洗行业中观察到最高浓度; (3)在钢铁,金属和干洗行业中,男性的三氯乙酸水平比女性高三倍; (4)年轻工人的三氯乙酸浓度高于年长工人; (5)在使用三氯乙烯的地区工作但未与三氯乙烯本身工作的人员,其尿中三氯乙酸水平也表明有接触。结论:日历年,行业类型,与TCE的接触程度,性别和年龄是丹麦工人尿液中TCA浓度的预测指标。

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