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首页> 外文期刊>Chemistry: A European journal >Highly Flexible Multifunctional Biopaper Comprising Chitosan Reinforced by Ultralong Hydroxyapatite Nanowires
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Highly Flexible Multifunctional Biopaper Comprising Chitosan Reinforced by Ultralong Hydroxyapatite Nanowires

机译：高度灵活的多功能生物素，包括由超羟基磷灰石纳米线加固的壳聚糖

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摘要

Highly flexible multifunctional biopaper comprising ultralong hydroxyapatite nanowires and chitosan (UHANWs/CS), with high weight fractions of ultralong hydroxyapatite nanowires (UHANWs) up to 100 wt. %, is reported. The as-prepared UHANWs/CS composite biopaper has high flexibility and superior mechanical properties even when the weight fraction of UHANWs is as high as 90 wt. %. In contrast, the control samples consisting of hydroxyapatite nanorods and chitosan (HANRs/CS) with weight fractions of HANRs higher than 66.7 wt.% cannot be obtained in the form of the flexible membrane. The ultimate tensile strength and Young's modulus of the UHANWs/CS composite biopaper are about 3.2 times and 4.3 times those of the HANRs/CS membrane with the same weight fraction of HAP, respectively. In addition, the UHANWs/CS composite biopaper (90 wt.% UHANWs) can be used for color printing using a commercial ink-jet printer. The surface wettability, swelling ratio, and water vapor transmission rate of the UHANWs/CS composite biopaper are adjustable by changing the addition amount of UHANWs. In vitro experiments indicate that the UHANWs/CS composite biopaper has good degradability, high acellular bioactivity and high biocompatibility. The asprepared UHANWs/CS composite biopaper is therefore promising for various biomedical applications such as wound dressing, bone-fracture fixation, and bone-defect repair.
机译：高度灵活的多功能生物植物，包括超羟基磷灰石纳米线和壳聚糖（UhanWs / Cs），具有高重量羟基磷灰石纳米线（UhanWs），高达100重量％。报告％。即使uhanWs的重量分数高达90重量％，AS制备的UHANWS / CS复合生物件也具有高柔韧性和优异的机械性能。 ％。相反，由羟基磷灰石纳米棒和壳聚糖（HANR / Cs）组成的对照样品，其HANR的重量分数高于66.7重量％。％不能以柔性膜的形式获得。 Uhanws / CS复合生物件的最终拉伸强度和杨氏模量分别具有相同的重量分数的HANR / CS膜的3.2倍和4.3倍。此外，Uhanws / CS复合生物件（90重量％的Uhanws）可用于使用商业喷墨打印机进行彩色印刷。通过改变UHANW的添加量，Uhanws / CS复合生物植物的表面润湿性，膨胀比和水蒸气透射率可调节。体外实验表明，UHANWS / CS复合生物素具有良好的降解性，高细胞生物活性和高生物相容性。因此，asprepared uhanws / cs复合Biopaper对各种生物医学应用有望，例如伤口敷料，骨折固定和骨缺损修复。

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  • 来源
    《Chemistry: A European journal》 |2017年第16期|共13页
  • 作者

    Tuan-Wei Sun; Ying-Jie Zhu; Feng Chen;

  • 作者单位

    State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 (P. R. China);

    State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 (P. R. China);

    State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 (P. R. China);

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 应用化学;
  • 关键词

    biomedical application; biopaper; chitosan; hydroxyapatite; nanowires;

    机译：生物医学应用;生物植物;壳聚糖;羟基磷灰石;纳米线;

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