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Nitrogen-Induced Transformation of Vitamin C into Multifunctional Up-converting Carbon Nanodots in the Visible- NIR Range

机译:氮气诱导的维生素C转化为可见载体范围内多功能上掺杂碳纳多

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摘要

Water-soluble, biocompatible, and photoluminescent carbon nanodots have been obtained from the rationalized carbonization of vitamin C, a well-known antioxidant molecule in the presence of an amine co-reactant. Herein, we describe the positive influence of N-doping to induce a unique pH-dependent lifetime decay response that would be potentially attractive in biological backgrounds with intrinsic fluorescence fluctuations. In addition, the selectivity and sensitivity of the N-containing carbon nanoprobes towards the detection of copper ions at ppm levels is critically enhanced in comparison with the un-doped counterpart, especially in the near-infrared (NIR) range. Finally, the up-converting properties have been also successfully applied to image tumor cells in the visible range and remarkably, in the NIR region in which minimal tissue or water absorption and maximum penetration depth are expected.
机译:在胺共反应物存在下,从维生素C的合理碳化碳化,从维生素C,众所周知的抗氧化分子中获得水溶性,生物相容性和光致发光碳纳米蛋白。 在此,我们描述了N-掺杂的积极影响诱导独特的pH依赖的寿命衰减响应,该衰减响应在具有内在荧光波动的生物背景中可能具有吸引力。 另外,与未掺杂的对应物相比,含N碳纳米素朝向PPM水平下检测PPM水平铜离子的选择性和敏感性,特别是在近红外(NIR)范围内。 最后,在可见范围内也已成功地应用于可见范围的图像肿瘤细胞,并且在预期最小组织或吸水和最大渗透深度的NIR区域中,可以显着地应用于可见范围的图像肿瘤细胞。

著录项

  • 来源
    《Chemistry: A European journal》 |2017年第13期|共7页
  • 作者单位

    Department of Chemical Engineering and Environmental Technology Institute of Nanoscience of Aragon (INA) University of Zaragoza 50018 Zaragoza (Spain);

    Department of Chemical Engineering and Environmental Technology Institute of Nanoscience of Aragon (INA) University of Zaragoza 50018 Zaragoza (Spain);

    Department of Physical Chemistry Faculty of Pharmacy University of Granada 18701 Granada (Spain);

    Department of Chemical Engineering and Environmental Technology Institute of Nanoscience of Aragon (INA) University of Zaragoza 50018 Zaragoza (Spain);

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 应用化学;
  • 关键词

    bioimaging; carbon; sensors; nanoparticles; upconversion;

    机译:生物体;碳;传感器;纳米粒子;上转换;

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