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首页> 外文期刊>Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides >Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications
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Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications

机译：基于纤维素纳米晶体和纤维素纳米纤维的生物医学应用水凝胶

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摘要

The production of cellulose nanomaterials from lignocellulosic biomass opens an opportunity for the development and application of new materials in nanotechnology. Over the last decade, cellulose nanomaterials based hydrogels have emerged as promising materials in the field of biomedical applications due to their low toxicity, biocompatibility, biodegradability, as well as excellent mechanical stability. In this review, recent progress on the preparation of cellulose nanocrystals (CNCs) and cellulose nanofibrils (CNFs) based hydrogels and their biomedical applications is summarized and discussed based on the analyses of the latest studies (especially for the reports in the past five years). We begin with a brief introduction of the differences in preparation methods and properties of two main types of cellulose nanomaterials: CNCs and CNFs isolated from lignocellulosic biomass. Then, various processes for the fabrication of CNCs based hydrogels and CNFs based hydrogels were elaborated, respectively, with the focus on some new methods (e.g. 3D printing). Furthermore, a number of biomedical applications of CNCs and CNFs based hydrogels, including drug delivery, wound dressings and tissue engineering scaffolds were highlighted. Finally, the prospects and ongoing challenges of CNCs and CNFs based hydrogels for biomedical applications were summarized. This work demonstrated that the CNCs and CNFs based hydrogels have great promise in a wide range of biomedical applications in the future.
机译：来自木质纤维素生物量的纤维素纳米材料的生产开辟了纳米技术新材料的开发和应用的机会。在过去的十年中，由于其低毒性，生物相容性，生物降解性以及优异的机械稳定性，纤维素纳米材料的水凝胶是在生物医学应用领域的有前途的材料。在该综述中，总结了基于纤维素纳米晶体（CNC）和纤维素纳米纤维（CNF）的水凝胶的近期基于最新研究的分析（特别是在过去五年的报告） 。我们首先简要介绍了两种主要类型纤维素纳米材料的制备方法和性质的差异：CNC和CNFS从木质纤维素生物质中分离。然后，分别阐述了对基于CNC的水凝胶和基于CNF的水凝胶的各种方法，重点是一些新方法（例如3D打印）。此外，突出了许多基于CNC和CNFS的水凝胶的生物医学应用，包括药物递送，伤口敷料和组织工程支架。最后，总结了CNCs和基于CNFS的生物医学应用水凝胶的前景和持续挑战。这项工作表明，CNC和基于CNFS的水凝胶在未来广泛的生物医学应用中具有很大的希望。

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