...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Colloids and Surfaces, A. Physicochemical and Engineering Aspects >Research of double emulsion formation and shell-thickness influence factors in a novel six-way junction microfluidic device
【24h】

Research of double emulsion formation and shell-thickness influence factors in a novel six-way junction microfluidic device

机译：一种新型六路接合微流体装置中双乳液形成和外壳厚度影响因素的研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The six-way junction microfluidic device has been widely used to prepare thin-shelled double emulsions as templates for liposomes. However, there is little numerical research of double emulsion formation in this device, and the influence factors of shell thickness still need to be further explored. In this paper, numerical simulations based on the VOF method are conducted to investigate double emulsion formation and shell-thickness influence factors in the six-way junction microfluidic device. Moreover, a new concept named relative shell thickness is proposed to intuitively reflect the relationship between the shell thickness and drop size. By the simulations, the double emulsion formation mechanisms at three typical flow regimes are revealed, including dripping, narrowing jetting, and widening jetting. The effects of operation parameters on the flow regime, double-emulsion droplet size and shell thickness are discussed. Results indicate that capillary numbers not only affect the flow regime but also the droplet size and shell thickness. It also finds that the effect of the middle fluid flow rate on the shell thickness is larger than the outer fluid flow rate and that the thin-shelled double emulsions are mainly generated in dripping. This paper reveals the change law of shell thickness with varied operation parameters and can guide for preparing double emulsions with controllable shell thickness in the six-way junction microfluidic device.
机译：六路结微流体装置已广泛用于制备薄壳的双乳液作为脂质体的模板。然而，在该装置中对双乳液形成几乎没有数值研究，仍然需要进一步探索壳体厚度的影响因素。本文采用了基于VOF法的数值模拟，研究了六途结微流体装置中的双乳液形成和壳厚度影响因子。此外，提出了一种名为相对壳厚度的新概念，以直观地反映壳体厚度和跌落尺寸之间的关系。通过模拟，揭示了三种典型流动制度的双乳液形成机制，包括滴落，缩小喷射和加宽喷射。讨论了操作参数对流动状态，双乳液液滴尺寸和壳厚度的影响。结果表明毛细管数不仅影响流动状态，还影响液滴尺寸和壳体厚度。它还发现，中间流体流速对外壳厚度的效果大于外部流体流速，并且薄壳的双乳液主要产生在滴水中。本文揭示了壳体厚度的变化规律，具有各种操作参数，可以在六径结微流体装置中制备具有可控壳厚度的双乳液。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号