Rice husk SiO2 (NPs) supported-BO3H3: a highly active, solvent-free and recyclable catalyst to dihydropyrimidin-2(1H)ones-(thiones) and coumarin-3-carboxylic acid synthesis

Khatavi S. Y.; Kantharaju K.; Yamanappa H.; Raghothama S.

首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Rice husk SiO2 (NPs) supported-BO3H3: a highly active, solvent-free and recyclable catalyst to dihydropyrimidin-2(1H)ones-(thiones) and coumarin-3-carboxylic acid synthesis

【24h】

Rice husk SiO2 (NPs) supported-BO3H3: a highly active, solvent-free and recyclable catalyst to dihydropyrimidin-2(1H)ones-(thiones) and coumarin-3-carboxylic acid synthesis

机译：稻壳SiO2（NPS）支持-BO3H3：对二氢嘧啶-2（1H）的高活性，无溶剂和可回收的催化剂 - （1H） - （象限）和香豆素-3-羧酸合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

3,4-Dihydropyrimidin-2(1H)ones(thiones) (DHPM) and coumarin-3-carboxylic acid are obtained in excellent to good yield by employing green catalyst under solvent-free condition. The condensation of substituted arylaldehyde, 1,3-diketoester and urea/thiourea in the presence of green catalyst after 1 h of stirring at 50 degrees C resulted in DHPM. The reaction of substituted o-hydroxybenzaldehyde with Meldrum's acid in the presence of catalyst under sonication for a few minutes gave coumarin-3-carboxylic acid. Here, we have used Lewis acid catalyst RHA-SiO2(NPs)-BO3H3 derived from the agro-waste of rice husk, a heterogeneous catalyst for important organic scaffold synthesis. The reaction required low catalyst loading (1.2 mg) to achieve a target product under solvent-free condition. A series of other derivatives of heterogeneous catalysts synthesized are RHA-SiO2, RHA-SiO2(NPs), RHA-SiO2-BO3H3. We examined their catalytic activity in the synthesis of DHPM and coumarin-3-carboxylic acid. Only the reaction catalysed by RHA-SiO2(NPs)-BO3H3 gave excellent yield of the product. The final isolated pure product has been fully characterized by various spectroscopic methods and confirmed.

机译：通过在无溶剂条件下采用绿色催化剂，获得3,4-二氢嘧啶-2（1H）（1H）（噻吩）（DHPM）和香豆素-3-羧酸。在50℃下搅拌1小时后，在绿色催化剂存在下，在50℃下搅拌后，取代芳基醛，1,3-二酮酯和尿素/硫脲的缩合导致DHPM。在超声处理的催化剂存在下将取代的O-羟基苯甲醛与Meldrum的酸的反应达几分钟，给了香豆素-3-羧酸。在这里，我们使用Lewis酸催化剂RHA-SiO 2（NPS）-BO3H3衍生自水稻壳的农用垃圾，是重要的有机支架合成的非均相催化剂。反应需要低催化剂负载（1.2mg），以在无溶剂条件下实现靶产物。合成的异构催化剂的一系列其他衍生物是RHA-SiO2，RHA-SiO 2（NPS），RHA-SiO2-BO3H3。我们在合成DHPM和香豆素-3-羧酸的合成中检查了它们的催化活性。仅通过RHA-SiO 2（NPS）-BO3H3催化的反应得到了优异的产物产率。最终孤立的纯产品已通过各种光谱方法完全表征并确认。

著录项

来源
《Current Science: A Fortnightly Journal of Research》 |2019年第11期|共14页
作者
Khatavi S. Y.; Kantharaju K.; Yamanappa H.; Raghothama S.;
展开▼
作者单位

Rani Channamma Univ Dept Chem Peptide &

Med Chem Res Lab NH-4 Belagavi 591156 India;

Rani Channamma Univ Dept Chem Peptide &

Med Chem Res Lab NH-4 Belagavi 591156 India;

Indian Inst Sci NMR Res Ctr Bengaluru 560012 Karnataka India;

Indian Inst Sci NMR Res Ctr Bengaluru 560012 Karnataka India;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类自然科学现状及发展;
关键词
Agro-waste; coumarin-3-carboxylic acid; dihydropyrimidin-2(1H)ones(thiones); heterogeneous catalyst; rice husk;

机译：农业废物;香豆素-3-羧酸;二氢嘧啶-2（1H）（1小时）;异构催化剂;稻壳;

相似文献

外文文献
中文文献
专利

1. Rice husk SiO2 (NPs) supported-BO3H3: a highly active, solvent-free and recyclable catalyst to dihydropyrimidin-2(1H)ones-(thiones) and coumarin-3-carboxylic acid synthesis [J] . Khatavi S. Y., Kantharaju K., Yamanappa H., Current Science: A Fortnightly Journal of Research . 2019,第11期

机译：稻壳SiO2（NPS）支持-BO3H3：对二氢嘧啶-2（1H）的高活性，无溶剂和可回收的催化剂 - （1H） - （象限）和香豆素-3-羧酸合成
2. Novel nano-titania embedded on graphite (nano-TiO2@C-g) as an efficient, eco-friendly, and recyclable catalyst for one-pot, solvent-free synthesis of 4-aryl-3,4-dihydroquinolin-2(1H)-ones, 3-methyl-4-aryl/alkyl-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones, and coumarin-3-carboxylic esters [J] . Nikoofar Kobra, Yielzoleh Fatemeh Molaei Research on Chemical Intermediates . 2018,第12期

机译：嵌入石墨（Nano-TiO2 @ Cg）的新型纳米二氧化钛作为一种罐的高效，环保和可回收催化剂，无溶剂合成4-芳基-3,4-二氢喹啉-2（1H） - 一种，3-甲基-4-芳基/烷基-2,4,5,7-四氢唑唑[3,4-B]吡啶-6-唑类，以及香豆素-3-羧酸酯
3. Lanthanide Triflate Catalyzed One-Pot Synthesis of Dihydropyrimidin-2(1H)-thiones by a Three-Component of 1,3-Dicarbonyl Compounds,Aldehydes,and Thiourea Using a Solvent-Free Biginelli Condensation [J] . Limin Wang, He Tian, Changtao Qian, Synthetic Communications . 2003,第9期

机译：无溶剂的Biginelli缩合反应由三组分1,3-二羰基化合物，醛和硫脲催化三氟化镧催化一锅法合成二氢嘧啶-2（1H）-硫酮
4. Coaled carbon-based solid acid: A new and efficient catalyst for click synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions [C] . Liu Wanyi, Ning Liu, Ruiyuan Zheng, International Conference on Chemical, Material and Metallurgical Engineering . 2013

机译：含有碳化碳固体酸：在无溶剂条件下单击合成3,4-二氢嘧啶-2（1H）酮的新增有效的催化剂
5. Synthesis of 34-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions [O] . Zahed Karimi-Jaberi, Mohammad Sadegh Moaddeli 2012

机译：在无溶剂条件下用三氯乙酸催化合成34-二氢嘧啶-2（1H）-一及其相应的2（1H）亚硫醚
6. Succinic Acid As a Green and Bio-Based Catalyst assisted solvent-free one-pot Biginelli synthesis of biologically active 3,4-dihydropyrimidin-2-(1H)-ones/thiones derivatives [O] . Farzaneh Mohamadpour, Mansoor Feilizadeh 2019

机译：琥珀酸作为绿色和生物基催化剂辅助溶剂无溶剂单罐Biginelli合成生物活性3,4-二氢嘧啶-2-（1H） - 酮/酮衍生物

Rice husk SiO2 (NPs) supported-BO3H3: a highly active, solvent-free and recyclable catalyst to dihydropyrimidin-2(1H)ones-(thiones) and coumarin-3-carboxylic acid synthesis

摘要

著录项

相似文献

相关主题

期刊订阅