• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Current Science: A Fortnightly Journal of Research >In vitro antioxidant and cytotoxic capacity of Kappaphycus alvarezii successive extracts
【24h】

In vitro antioxidant and cytotoxic capacity of Kappaphycus alvarezii successive extracts

机译：kappaphycus alvarezii连续提取物的体外抗氧化和细胞毒性容量

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Kappaphycus alvarezii, marine red algae was collected from the Mandapam coastal region, Tamil Nadu, India to examine cytotoxic and redox capacity of its extracts. HPLC analysis indicates the presence of phenolic compounds in the methanolic extract. The maximum phenol content measured as mg of gallic acid standard equivalent was found to be 86.45 +/- 70.72 mg/ml extract. The total flavonoid content was found to be 85.52 +/- 32.57 mg/ml in the extract (using quercetin as a standard). The antioxidant potential of the extracts was determined by employing DPPH scavenging assay and antioxidant assay using the phosphomolybdenum method. Methanolic extract demonstrated efficient antioxidant capacity and DPPH radical scavenging activity. GC-MS analysis was carried out in crude extracts of K. alvarezii. MTT assay showed that the extracts are toxic to HeLa cells and their IC50 value was 1.75 mg/ml. The study shows that different extracts of K. alvarezii have strong antioxidant and less cytotoxic activity against HELA cells.
机译：Kappaphycus Alvarezii，海洋红藻是从印度泰米尔纳德邦的曼达纳姆沿海地区收集的，以研究其提取物的细胞毒性和氧化还原能力。 HPLC分析表明甲醇提取物中存在酚类化合物。发现为Mg的Galic酸标准当量测量的最大酚含量为86.45 +/- 70.72mg / ml提取物。在提取物中发现总黄酮含量为85.52 +/- 32.57mg / ml（使用槲皮素作为标准）。通过使用磷钼法采用DPPH清除测定和抗氧化剂测定来测定提取物的抗氧化潜力。甲烷醇提取物证明了有效的抗氧化能力和DPPH激进的清除活性。 GC-MS分析在K.Alvarezii的粗提物中进行。 MTT测定表明，提取物对Hela细胞有毒，其IC50值为1.75mg / ml。该研究表明，K.Alvarezii的不同提取物具有强烈的抗氧化剂和对Hela细胞的细胞毒性活性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号