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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Detection of tumour in biological tissues by laser backscattering and transillumination signal analysis
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Detection of tumour in biological tissues by laser backscattering and transillumination signal analysis

机译：激光反向散射和多云化信号分析检测生物组织中的肿瘤

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The onset of tumour in biological tissues affects their optical properties. In the present study Monte Carlo simulation of the diffuse surface reflectance and transmittance for detection of the inhomogeneities/tumour in control tissue is carried out. From the isolated heart, spleen and adipose tissues of goat digital phantoms are prepared. The virtual optical probe consists of a photon injection port (source), three ports placed along the x-axis at 2, 4 and 6 mm to collect backscattered photons and one port placed coaxially to the source port at the exit end to collect transmitted photons. Two types of inhomogeneities of diameter 2 mm are introduced in the phantoms first a tissue of absorption coefficient 10% more than that of heart and same scattering coefficient; second, adipose or spleen tissue, embedded in heart phantoms, at depths 2, 4 and 6 mm. The inhomogeneity placed at depth 2 mm gives maximum normalized backscattered intensity ([NBI]) at the port placed at 2 mm. The maxima of low [NBI]s are also observed at ports located at 4 and 6 mm of inhomogeneities embedded at depths 4 and 6 mm. The signals due to high scattering and high absorption are positive and negative with reference to that of heart. The transmittance also shows respective variations with placement of tissues in the phantoms. The normalized transmitted intensity is maximum when the tissues are placed close to the exit surface. These are further characterized by the peak intensity and full-width at half maximum of signals. The data analysis provides details of their type, location and size. Inhomogeneities with minimal change in optical parameters are also identified.
机译：生物组织中的肿瘤发作影响它们的光学性质。在本研究中，进行了对控制组织中的漫射表面反射率和透射率的蒙特卡罗模拟，用于检测控制组织中的不均匀性/肿瘤。从孤立的心脏，制备山羊数码幽灵的脾脏和脂肪组织。虚拟光学探针由光子注入端口（源）组成，沿2,4和6mm的X轴放置的三个端口，以收集反向散射的光子，并且一个端口同轴地放置在出射端的源端口以收集传输的光子。在幻影中引入两种类型的直径2mm的不均匀性首先是吸收系数的组织比心脏和相同的散射系数大。第二，脂肪或脾组织，嵌入心脏幻影，深度2,4和6mm。放置在深度2 mm处的不均匀性在放置在2mm处的端口处提供最大归一化的反向散射强度（[NBI]）。在位于嵌入在深度4和6mm的深度的4和6mm的不均匀性的端口，也观察到低λs的最大值。引起高吸收引起的信号是阳性和阴性的，参照心脏。透射率还显示出与模组中的组织放置的相应变化。当组织靠近出射表面时，归一化透射强度最大。这些进一步的特征在于，在信号的一半最大的峰值强度和全宽。数据分析提供了其类型，位置和大小的详细信息。还识别了光学参数变化最小的不均匀性。

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