...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ACS applied materials & interfaces >Dye-Loaded Quatsomes Exhibiting FRET as Nanoprobes for Bioimaging
【24h】

Dye-Loaded Quatsomes Exhibiting FRET as Nanoprobes for Bioimaging

机译：染料装载的纯页，作为BioMimaging的纳米诡计

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Fluorescent organic nanoparticles (FONs) are emerging as an attractive alternative to the well-established fluorescent inorganic nanoparticles or small organic dyes. Their proper design allows one to obtain biocompatible probes with superior brightness and high photostability, although usually affected by low colloidal stability. Herein, we present a type of FONs with outstanding photophysical and physicochemical properties in-line with the stringent requirements for biomedical applications. These FONs are based on quatsome (QS) nano-vesicles containing a pair of fluorescent carbocyanine molecules that give rise to Forster resonance energy transfer (FRET). Structural homogeneity, high brightness, photostability, and high FRET efficiency make these FONs a promising class of optical bioprobes. Loaded QSs have been used for in vitro bioimaging, demonstrating the nanovesicle membrane integrity after cell internalization, and the possibility to monitor the intracellular vesicle fate. Taken together, the proposed QSs loaded with a FRET pair constitute a promising platform for bioimaging and theranostics.
机译：荧光有机纳米颗粒（FONS）被出现为具有良好良好的荧光无机纳米颗粒或小有机染料的有吸引力的替代品。它们适当的设计允许人们获得具有优异亮度和高光稳定性的生物相容性探针，尽管通常受低胶体稳定性的影响。在此，我们呈现了一种具有优异的光药和物理化学特性的粉丝，与生物医学应用的严格要求。这些FONS基于含有一对荧光碳氰基分子的丙崩（QS）纳米囊泡，其产生福尔斯特共振能量转移（FRET）。结构均匀性，高亮度，光稳定性和高褶皱效率使这些FON成为一类有前途的光学生物软木。已加载的QSS已用于体外消影，在细胞内化后展示纳米粒子膜完整性，以及监测细胞内囊泡命运的可能性。占据了装载FRET对的建议QS，构成了一个有希望的生物体和治疗器平台。

著录项

  • 来源
    《ACS applied materials & interfaces》 |2020年第18期|共10页
  • 作者

    Morla-Folch Judit; Vargas-Nadal Guillem; Zhao Tinghan; Sissa Cristina; Ardizzone Antonio; Kurhuzenkau Siarhei; Kober Mariana; Uddin Mehrun; Painelli Anna; Veciana Jaume; Belfield Kevin D.; Ventosa Nora;

  • 作者单位

    New Jersey Inst Technol Coll Sci &

    Liberal Arts Dept Chem &

    Environm Sci Newark NJ 07102 USA;

    CSIC Inst Ciencia Dels Mat Barcelona ICMAB Campus UAB Cerdanyola Del Valles 08193 Spain;

    New Jersey Inst Technol Coll Sci &

    Liberal Arts Dept Chem &

    Environm Sci Newark NJ 07102 USA;

    Univ Parma Dipartimento Sci Chim Vita &

    Sostenibilita Ambien I-43124 Parma Italy;

    CSIC Inst Ciencia Dels Mat Barcelona ICMAB Campus UAB Cerdanyola Del Valles 08193 Spain;

    Univ Parma Dipartimento Sci Chim Vita &

    Sostenibilita Ambien I-43124 Parma Italy;

    CSIC Inst Ciencia Dels Mat Barcelona ICMAB Campus UAB Cerdanyola Del Valles 08193 Spain;

    New Jersey Inst Technol Coll Sci &

    Liberal Arts Dept Chem &

    Environm Sci Newark NJ 07102 USA;

    Univ Parma Dipartimento Sci Chim Vita &

    Sostenibilita Ambien I-43124 Parma Italy;

    CSIC Inst Ciencia Dels Mat Barcelona ICMAB Campus UAB Cerdanyola Del Valles 08193 Spain;

    New Jersey Inst Technol Coll Sci &

    Liberal Arts Dept Chem &

    Environm Sci Newark NJ 07102 USA;

    CSIC Inst Ciencia Dels Mat Barcelona ICMAB Campus UAB Cerdanyola Del Valles 08193 Spain;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学工业;
  • 关键词

    bioimaging; fluorescent organic nanoparticles; FRET; quatsomes; bioprobes;

    机译：生物体;荧光有机纳米颗粒;褶皱;纯页;生物软管;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号