首页> 外文期刊>American Journal of Physiology >NLRP3 inflammasome mediates white adipose tissue browning after bum
【24h】

NLRP3 inflammasome mediates white adipose tissue browning after bum

机译:NLRP3炎症介导白脂肪脂肪组织褐变后

获取原文
获取原文并翻译 | 示例
           

摘要

A hallmark after burn is the stress and inflammatory-induced hypermetabolic response. Recently, we and others found that browning of white adipose tissue (WAT) is a critical component of this complex detrimental response. Although browning and inflammation have been independently delineated to occur after injury, their interaction is currently not well defined. One of the master regulators of inflammation and adipose tissue remodeling after burns is nucleotide-binding and oli-gomerization domain, leucine rich repeat and pyrin domain containing 3 (NLRP3) inflammasome. The aim of this this study was to determine whether NLRP3 modulates and activates WAT browning after burn.
机译:烧伤后的标志是压力和炎症诱导的超代谢反应。 最近,我们和其他人发现白色脂肪组织(WAT)的褐变是这种复杂不利反应的关键组成部分。 虽然在损伤后发生褐变和炎症已经独立描绘,但它们的相互作用目前没有明确定义。 燃烧后炎症和脂肪组织重塑的炎症和脂肪组织的一种重组之一是核苷酸结合和Oli-gomerization结构域,含有3(NLRP3)炎症的少氨酸富重复和吡啶结构域。 本研究的目的是确定NLRP3是否在燃烧后调节并激活Wat褐变。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号