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Hemodynamic and perceptual responses to blood flow-restricted exercise among patients undergoing dialysis

机译:透析患者血液流动限制运动的血流动力学和感知反应

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摘要

End-stage kidney disease (ESKD) is associated with reduced exercise capacity, skeletal muscle atrophy, and impaired physical function (22). These deficiencies can be improved with aerobic and/or resistance exercise training performed during hemodialysis (HD) where low- to moderate-intensity exercise is considered safe and well tolerated (6, 9, 20, 47, 49, 50). However, not all studies using traditional exercise, in particular aerobic exercise alone, result in marked improvements in muscle size, strength, exercise capacity, or physical function, and rarely are improvements observed across all of these physiological domains (18, 50). This is compounded by exercise not being widely adopted among patients with ESKD, with most patients displaying a significant reluctance to exercise (8, 28). Proposed exercise interventions therefore need to be safe, tolerable, and, at a minimum, similarly efficacious than the current alternatives.
机译:末期肾病(ESKD)与运动能力,骨骼肌萎缩和受损物理功能(22)有关。 在血液透析期(HD)中进行的有氧和/或电阻运动训练可以改善这些缺陷,其中低于中等强度运动被认为是安全且耐受性良好的(6,9,20,47,49,50)。 然而,并非所有使用传统运动的研究,特别是单独使用的有氧运动,导致肌肉大小,强度,运动能力或物理功能的显着改善,并且很少观察到所有这些生理域(18,50)的改进。 这通过运动不被广泛采用ESKD,大多数患者均为显着不情愿地进行锻炼(8,28)。 因此,拟议的运动干预措施需要安全,可容忍,并且比目前的替代方案相似,并且均可相似。

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