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Letter to the Editor: Combined effects of hypoxia and heat: importance of hypoxic dose

机译：致编辑的信：缺氧和热量的效果：缺氧剂量的重要性

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to the editor: We congratulate Rendell and colleagues (9) on a nicely executed crossover study regarding (he combined effects of heat and hypoxic acclimation on exercise performance in temperate conditions. They clearly demonstrate that during a heat acclimation protocol the addition of a concomitant nocturnal hypoxic exposure does not provide any benefits to performance in normoxic environment. Whereas we concur with the authors' findings, we would advise caution regarding such a general conclusion. Namely, the hypoxia-induced increment in erythropoietin (EPO) concentration would suggest that the hypoxic acclimation protocol was either insufficient or that the acclimation to hypoxia was perhaps confounded by the concomitant acclimation to heat. The authors interpreted their findings assuming that the hypoxic acclimation did not affect the acclimation to heat. However, on the basis of the observed EPO responses, one might also conclude that acclimation to hypoxia was impaired by the concomitant heat acclimation.
机译：到编辑：我们祝贺Rendell及其同事（9）关于一个很好的执行交叉研究（他在温带条件下综合热量和缺氧适应对运动性能的综合作用。它们清楚地证明，在热处理方案期间添加伴随的夜间缺氧暴露对常氧环境中的表现不提供任何益处。而我们同意作者的调查结果，我们会向谨慎提出谨慎的是，促进促红细胞生成素（EPO）浓度的缺氧诱导的增量表明缺氧适应方案要么不充分，或者对缺氧的适应可能被伴随到热量伴有。作者解释了他们的发现，假设缺氧驯化并没有影响加热的适应性。然而，在观察到的EPO反应的基础上，还有人还可以得出结论，对缺氧的适应由CO损害ncomitant热驯化。

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